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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Enclomiphene restart - how long?
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<blockquote data-quote="madman" data-source="post: 275874" data-attributes="member: 13851"><p>The exogenous T (TC/TE) is already out of your system.</p><p></p><p>Need to give it more time (3-6 months).</p><p></p><p></p><p></p><p></p><p><strong>Conclusions</strong></p><p><strong></strong></p><p><strong><em>CC is a compelling option to treat male hypogonadism, although a chronic treatment is needed in most patients. <u>About one in every four patients respond to a CC short trial to "reboot" the HPT axis physiology</u>. Further understanding of TT kinetics in these patients in the long term is warranted.</em></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>Conclusions</strong></p><p><strong></strong></p><p><strong><em>In men prescribed CC for fertility optimization, <u>we observed a maximal improvement in TT at 6 months, followed by a plateau</u>. <u>Sperm concentrations showed a statistically significant improvement at 9 months</u>. <u>Our results suggest that a longer duration of CC therapy may be needed to fully appreciate the benefit of CC treatment</u>. Our study is limited by retrospective analysis, absence of controls, and small sample size. Work is underway to examine long-term follow-up data of CC in men seeking treatment for hypogonadism rather than optimization of fertility.</em></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>CONCLUSIONS</strong></p><p><strong></strong></p><p><strong><em>Overall, our study raises the question of what a suitable endpoint may be when studying CC monotherapy in the context of male subfertility and hypogonadism. <u>We pose that 6 months of CC may be needed to achieve maximal benefit in TT while 9 months may be necessary to observe statistical benefit in sperm concentration</u>. The findings from this work may serve as additional data for reproductive urologists to use to counsel men regarding the potential benefits of CC monotherapy for subfertility.</em></strong></p><p></p><p></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/threads/would-i-be-making-a-mistake.28608/page-2#post-267306[/URL]</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/threads/clomiphene-citrate-a-potential-alternative-for-tth-in-hypogonadal-males.27343/[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 275874, member: 13851"] The exogenous T (TC/TE) is already out of your system. Need to give it more time (3-6 months). [B]Conclusions [I]CC is a compelling option to treat male hypogonadism, although a chronic treatment is needed in most patients. [U]About one in every four patients respond to a CC short trial to "reboot" the HPT axis physiology[/U]. Further understanding of TT kinetics in these patients in the long term is warranted.[/I] Conclusions [I]In men prescribed CC for fertility optimization, [U]we observed a maximal improvement in TT at 6 months, followed by a plateau[/U]. [U]Sperm concentrations showed a statistically significant improvement at 9 months[/U]. [U]Our results suggest that a longer duration of CC therapy may be needed to fully appreciate the benefit of CC treatment[/U]. Our study is limited by retrospective analysis, absence of controls, and small sample size. Work is underway to examine long-term follow-up data of CC in men seeking treatment for hypogonadism rather than optimization of fertility.[/I] CONCLUSIONS [I]Overall, our study raises the question of what a suitable endpoint may be when studying CC monotherapy in the context of male subfertility and hypogonadism. [U]We pose that 6 months of CC may be needed to achieve maximal benefit in TT while 9 months may be necessary to observe statistical benefit in sperm concentration[/U]. The findings from this work may serve as additional data for reproductive urologists to use to counsel men regarding the potential benefits of CC monotherapy for subfertility.[/I][/B] [URL unfurl="true"]https://www.excelmale.com/threads/would-i-be-making-a-mistake.28608/page-2#post-267306[/URL] [URL unfurl="true"]https://www.excelmale.com/threads/clomiphene-citrate-a-potential-alternative-for-tth-in-hypogonadal-males.27343/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Enclomiphene restart - how long?
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