ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
General Health & Fitness
Nutrition and Supplements
Effects of High vs Low Glycemic Index of Dietary Carb on Cardiovascular Disease Risk Factors
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Vince" data-source="post: 23148" data-attributes="member: 843"><p>Another possibility, suggested by <a href="http://www.excelmale.com/wiki/Linus_Pauling" target="_blank">Linus Pauling</a>, is that Lp(a) is a primate adaptation to <a href="http://www.excelmale.com/wiki/L-gulonolactone_oxidase" target="_blank">L-gulonolactone oxidase</a> (GULO) deficiency, found only in certain lines of mammals. GULO is required for converting <a href="http://www.excelmale.com/wiki/Glucose" target="_blank">glucose</a> to <a href="http://www.excelmale.com/wiki/Ascorbic_acid" target="_blank">ascorbic acid</a> (vitamin C), which is needed to repair arteries; following the loss of GULO, those primates that adopted diets less abundant in vitamin C may have used Lp(a) as an ascorbic-acid surrogate to repair arterial walls.</p><p></p><p></p><p>However, individuals without Lp(a) or with very low Lp(a) levels seem to be healthy. Thus, plasma Lp(a) is not vital, at least under normal environmental conditions. Since apo(a)/Lp(a) derived rather recently in mammalian evolution - only old world monkeys and humans have been shown to harbour Lp(a) - its function might not be vital but just evolutionarily advantageous under certain environmental conditions, e.g. in case of exposure to certain infectious diseases.</p></blockquote><p></p>
[QUOTE="Vince, post: 23148, member: 843"] Another possibility, suggested by [URL="http://www.excelmale.com/wiki/Linus_Pauling"]Linus Pauling[/URL], is that Lp(a) is a primate adaptation to [URL="http://www.excelmale.com/wiki/L-gulonolactone_oxidase"]L-gulonolactone oxidase[/URL] (GULO) deficiency, found only in certain lines of mammals. GULO is required for converting [URL="http://www.excelmale.com/wiki/Glucose"]glucose[/URL] to [URL="http://www.excelmale.com/wiki/Ascorbic_acid"]ascorbic acid[/URL] (vitamin C), which is needed to repair arteries; following the loss of GULO, those primates that adopted diets less abundant in vitamin C may have used Lp(a) as an ascorbic-acid surrogate to repair arterial walls. However, individuals without Lp(a) or with very low Lp(a) levels seem to be healthy. Thus, plasma Lp(a) is not vital, at least under normal environmental conditions. Since apo(a)/Lp(a) derived rather recently in mammalian evolution - only old world monkeys and humans have been shown to harbour Lp(a) - its function might not be vital but just evolutionarily advantageous under certain environmental conditions, e.g. in case of exposure to certain infectious diseases. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
X (Twitter)
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
General Health & Fitness
Nutrition and Supplements
Effects of High vs Low Glycemic Index of Dietary Carb on Cardiovascular Disease Risk Factors
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top