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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Does Modafinil Work For Energy?
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<blockquote data-quote="Nelson Vergel" data-source="post: 70051" data-attributes="member: 3"><p><a href="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue" target="_blank"><strong>Modafinil-Induced Changes in Functional Connectivity in the Cortex and Cerebellum of Healthy Elderly Subjects</strong></a></p><p><a href="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue" target="_blank"></a></p><p><strong>Conclusion</strong></p><p></p><p><span style="color: #3E3D40"><span style="font-family: 'Georgia'">The potential therapeutic implication of modafinil use in the elderly can especially be envisioned when considering aging- or Alzheimer's disease (AD)-dependent cognitive deficits.</span></span></p><p><span style="color: #3E3D40"><span style="font-family: 'Georgia'"></span></span></p><p><span style="color: #3E3D40"><span style="font-family: 'Georgia'">Upon brain aging, cognitive deficiency can result from failure of inhibitory processes and the dysfunctional interplay between the WM and the attentional systems (<a href="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B30" target="_blank">Luis et al., 2015</a>). This dysfunction can result in an overall reduced activity of filtering relevant information while increasing the production of noise overflow (<a href="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B30" target="_blank">Luis et al., 2015</a>). A similar deficit in cognitive control has been found to occur in mild cognitive impairment (MCI) or early-stage dementia patients. Thus, on a speculative note, the modafinil-driven FC effects we are reporting to occur in areas that are controlling attention and inhibitory control may help to counteract deficits of the aging brain as well as in the brain of MCI or AD patients.</span></span></p><p><span style="color: #3E3D40"><span style="font-family: 'Georgia'"></span></span></p><p><span style="color: #3E3D40"><span style="font-family: 'Georgia'">Interestingly, recent data indicate that AD-related neurodegeneration is present, beyond the cortex, also in the Crus I and II cerebellar regions (<a href="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B25" target="_blank">Guo et al., 2016</a>). In that respect, it is conceivable that the modafinil FC effects we have found in these cerebellar areas may be of some help and exert a compensatory role.</span></span></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 70051, member: 3"] [URL="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue"][B]Modafinil-Induced Changes in Functional Connectivity in the Cortex and Cerebellum of Healthy Elderly Subjects[/B] [/URL] [B]Conclusion[/B] [COLOR=#3E3D40][FONT=Georgia]The potential therapeutic implication of modafinil use in the elderly can especially be envisioned when considering aging- or Alzheimer's disease (AD)-dependent cognitive deficits. [/FONT][/COLOR] [COLOR=#3E3D40][FONT=Georgia]Upon brain aging, cognitive deficiency can result from failure of inhibitory processes and the dysfunctional interplay between the WM and the attentional systems ([URL="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B30"]Luis et al., 2015[/URL]). This dysfunction can result in an overall reduced activity of filtering relevant information while increasing the production of noise overflow ([URL="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B30"]Luis et al., 2015[/URL]). A similar deficit in cognitive control has been found to occur in mild cognitive impairment (MCI) or early-stage dementia patients. Thus, on a speculative note, the modafinil-driven FC effects we are reporting to occur in areas that are controlling attention and inhibitory control may help to counteract deficits of the aging brain as well as in the brain of MCI or AD patients. [/FONT][/COLOR] [COLOR=#3E3D40][FONT=Georgia]Interestingly, recent data indicate that AD-related neurodegeneration is present, beyond the cortex, also in the Crus I and II cerebellar regions ([URL="http://journal.frontiersin.org/article/10.3389/fnagi.2017.00085/full?utm_campaign=Revue%20newsletter&utm_medium=Newsletter&utm_source=revue#B25"]Guo et al., 2016[/URL]). In that respect, it is conceivable that the modafinil FC effects we have found in these cerebellar areas may be of some help and exert a compensatory role.[/FONT][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Does Modafinil Work For Energy?
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