Not sure if this is the right forum. I did try to search. Can anyone recommend an overseas pharmacy for Noncontrolled meds other than ReliablepharmacyRX? Thank you
Important lessons about testosterone therapy- weight loss vs. testosterone therapy for symptom resolution, classical vs. functional hypogonadism, and short-term vs. lifelong testosterone therapy
In this commentary, we highlight important findings from a notable RCT by Ng Tang Fui et al. 2016...
Inhibitors of 5alpha-steroid reductase are drugs used to treat androgen-dependent conditions including prosta...te diseases and androgenic alopecia. Finasteride was the first on the market and is currently the most widely used inhibitor. Dutasteride was the second inhibitor to be approved and...
Gentlemen, I thought that this was interesting
Currently, there is no consensus regarding the expected concentration levels of intra-prostatic sex steroids in patients with Prostate Cancer (PCa). Our objective was to assess the concentration levels of sex steroids in prostatic tissue and...
I see there is some confusion over TRT and prostate cancer. So, I wanted to try to help clarify.
For years it was accepted as a fact that androgens caused prostate cancer (PC), but new evidence has changed that view. Newer studies show that PC occurs in men with low T as often as those with...
Have you seen this study
Androgen receptors beyond prostate cancer: an old marker as a new target
Javier Munoz, Jennifer J. Wheler, and Razelle Kurzrock
Abstract
Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary...
I have used the search feature but cannot seem to find anything.
Has anyone used an aromatase inhibitor as monotherapy for TRT? If so, how was your experience?
We obviously are familiar with Clomid as therapy. MY understanding as to how that works is that the clomid hides estrogen from the...
TRT often results in complete shut down of luetinizing hormone (LH). With very low or no LH, the testes receive little or no stimulation (to produce Test) resulting in reduced fertility and teste size. In addition, some hypothesize that LH may have a function other than instructing the testes...
Male sexual function can be maintained without aromatization: randomized placebo-controlled trial of dihydrotestosterone (DHT) in healthy, older men for 24 months.
Sartorius GA1, Ly LP, Handelsman DJ.
1Andrology Department, Concord Hospital, Sydney, NSW, Australia; ANZAC Research Institute...
I have used the search function but haven't been able to find the answer
Does anyone have lab evidence of a raise in DHT that's disproportionately greater than the related increase in T. Or do you know of any reason why this could happen?
i realize that DHT is not evil, and that elevated DHT...
Generally, Doctors who advocate TRT seem to subscribe to the theory of Androgen Receptor (AR) suturation. Under this theory, the ARs in the prostate are fully saturated at total testosterone levels of 150. And thus, a testosterone level 1,200 is no more likely to cause malignant or benign...
If you have added DHEA, 7-keto DHEA or pregnenolone to your regimen, what has the effect been to (1) your sense of well being and (2) your labs. Thanks !!
SAN DIEGO — A novel oral testosterone formulation (LPCN 1021, Lipocine), which was shown to be safe and effective at 13 weeks, continues to demonstrate similar results at 52 weeks, according to new data.
The formulation is currently under review at the US Food and Drug Administration (FDA)...
I have heard that more frequent injections may result in less conversion to E2 and better control of HCT. I have also heard that more frequent injections can result in a smaller total dose for the week. For example, someone injecting 150 per week may only need 16 per day (total of 112 for the...
Has anyone attempted to lower their SHBG with the intention for raising free T? What were your results?
I realize that doing so would also free up E2. I also understand Dr John's position. Thanks
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