Testosterone and Male Pubertal Maturation

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Testosterone and Male Pubertal Maturation

Presentation to the Pediatric Advisory
Committee


8 April 2019

by
Alan D. Rogol, M.D., Ph.D.
Professor Emeritus Pediatrics and Pharmacology
University of Virginia
Charlottesville, VA





Agenda

Background
• Physiology of the HPG axis in boys at puberty
• Estimate of number of adolescents who may require testosterone
• Challenges in designing and operationalizing studies of testosterone therapy in adolescents
• Conclusions







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