When I started, my HCT was in the upper 40s, maybe 47-48 range. I was started on a generic protocol of 140mg Test Cyp IM once per week, 750 IU HcG once per week, and 2mg anastrozole per week. Shocker alert, the anastrozole smashed my estrogen. I backed off to .5mg per week and it was still too much. I have never really got a dosing schedule that worked with anastrozole. It just nukes my e2. I just allow my E2 drift slowly towards being too high and take a .5mg dose or use a little aromasin 6.25mg PRN.
When I initially began therapy, My HCT jumped to 51 within a couple of months so I was backed down to 120mg once per week. So yes I’ve battled high HCT since starting therapy. Interestingly, my cardio is GREAT with a higher HCT so I’m torn as to if it matters so much or not. I refuse to let it run wild though.
I have since switched to a local clinic with a PA friend who manages my care but allows me to experiment with dosing schedules etc. A dose of 140 mg per week in two doses provides me a good result. I don’t use HCG anymore and rarely use a AI. I still have to watch HCT as it will drift north into the low to mid 50s. I usually donate power reds every 4 months to keep in range and keep the peace with my provider.
I would love to experiment more with the Vork protocol to see what I can do with HCT and ferritin management. I tried it one time and brought my ferritin from 7 to 35 so it worked. I have also tried other anecdotal things (Telmisartan, grapefruit daily, etc) with little to no benefit.
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