Phase II clinical study for SPONTAN rapid-acting intranasal spray for the treatment of erectile dysfunction

[madman]

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www.theaustralian.com.au

 

[madman]

Thread 'Breakthrough Intranasal ED Treatments: How ROXUS® and SPONTAN® Offer New Hope for Men Facing Side Effects from Oral Medications'

Aug 30, 2025

* Dr Andrew Sun, said: "A sizeable portion of patients experience problematic side effects from higher-dose PDE5 tablets –back pain, heartburn, joint aches–that affect quality of life and intimacy. ROXUS AND SPONTAN offer the rapid onset men want without the systemic side effects that often compromise their experience. I’m looking forward to introducing these options in my practice as they become available in the US.




Highlights

• Leading Texas urologist from one of the state’s largest men’s health clinics joins LTR Pharma's Scientific...

• madman
• ed; nasal spray; spontan/roxus
• Replies: 6
• Forum: When TRT Is Not Enough (ED, Libido, & More)

 

[Nelson Vergel]

Thread 'Game-Changer for Men: New ED Nasal Spray Works in Just 10 Minutes – Independent Study Validates SPONTAN'

Aug 30, 2025

https://www.theaustralian.com.au/business/stockhead/content/clinical-data-for-ltr-pharmas-ed-nasal-spray-published-in-peerreviewed-journal/news-story/e02495d17c9fc3d21c8dedda88f91b3b

Key clinical findings included:

• Ultra-rapid onset – SPONTAN reached peak plasma concentration (Tmax) in a median of 10 minutes versus 45 minutes for oral tablets, with mean values of 12 minutes versus 56 minutes respectively.
• Superior efficiency – Despite half the dose, SPONTAN achieved higher bioavailability per milligram, with dose-normalised...

• madman
• ed; nasal spray; spontan/roxus
• Replies: 2
• Forum: When TRT Is Not Enough (ED, Libido, & More)