New Guy help appreciated it

[Nick23]

Any info would be appreciated and I'm sure you all have heard it all thanks.

37 M Did steriods early 20s' have not touched them since. LOW T have been getting treated for injections twice a week levels have got to normal even over 1000 obvously they go down as the two weeks go on looking into test implant. So went to NUMALE Clinic for second opion. They want to put on trimix 3 weekly even if no intercourse saying it helps get the blood going and erections etc.. They gave a test shot in office and obvioulsy not the right dose needed more. Was born with a bad heart valve replaced 3 years ago got a new one. On 2 BP meds going to see Cardiologist again in 3 weeks perhaps changing them. Tried viagra, cialais etc.. Not much help I see the Trimix works from reading on here. My question is what NuMALE suggested taking 3 weekly to get blood flowing is correct? I know the BP meds could be causing the ED also and did have an issue with pelvic floor before. Anyway totally lost not sure which way to go.

 

[Vince]

Nick Hi, many people here have used trimix but I have never used it. It sounds like it works and many people have very good results. When you have time check out the posts on trimix.https://www.excelmale.com/forum/showthread.php?402-Penis-Injections-for-Hard-Erections-TRIMIX

 

[Nick23]

My Endo won't prescribe HCG so basically what I am reading is I need to be on HCG would not being on it make that big of a difference with ED thanks.

 

[Nelson Vergel]

TRIMIX should not be used as a way to improve flood flow. Shame on them!!

Frequent use of TRIMIX can actually decrease flood flow to the penis by causing fibrosis and calcium deposits, specially if the product is not spread well throughout the shaft.

For improved blood flow and decrease of fibrosis risks, taking daily low dose Cialis is the way to go. You may want to discuss with your urologist and cardiologist the concurrent use of a low dose of an alpha blocker like Doxasozin with 5- 10 mg Cialis to not only improve penile blood flow but also blood pressure. Keep in mind that these two drugs may have additive effect on ED and BP, so it is important to dose them correctly to avoid low blood pressure episodes.

I would use TRIMIX only when I want to have sex.

******************

The Choice of Antihypertensive Drugs in Patients With Erectile Dysfunction


The link between HT and ED is even more complex because ED is a side-effect of certain anti-hypertensives.[SUP][10,11][/SUP] This is best illustrated by the Treatment of Mild Hypertension Study (TOMHS)[SUP][11][/SUP] that included 557 hypertensive men aged 45-69 years. They received a placebo or one of five drugs: acebutolol, amlodipine, chlorthalidone, doxazosin or enalapril. Sexual function was assessed at baseline and annually during follow-up (48 months). At baseline, 14.4% of the men reported problems with sexual function. ED was positively related to age, systolic blood pressure and previous use of an anti-hypertensive agent.
This a-blocker is probably the anti-hypertensive with the best-documented beneficial effect on erectile function. In TOMHS,[SUP][11][/SUP] the incidence of ED was lowest in patients using doxazosin and highest in those on chlorthalidone (a thiazide-like diuretic). The disappearance of ED was greater in the doxazosin group (87.5%) than for all the other drugs combined (55%).[SUP][11][/SUP] However, this effect did not achieve statistical significance. Furthermore, a small study has shown that the co-administration of doxazosin, orally, to patients who did not have a good response to intracavernosal alprostadil, resulted in a significant improvement in the response to this prostaglandin E1 analogue.[SUP][10,17][/SUP] There is also evidence that the intracavernosal injection of doxazosin in monkeys has a significant effect on penile function.[SUP][10][/SUP]
Another indication for doxazosin is benign prostatic hyperplasia (BPH).[SUP][18][/SUP] Almost 50% of all men aged 60-69 years in the UK have symptomatic BPH.[SUP][18,19][/SUP] Therefore the expected concomitant incidence of ED, HT and BPH makes doxazosin a very useful drug in older men. In addition, the introduction of doxazosin may obviate the need for the treatment of ED and may even potentiate the therapeutic impact of any specific treatment for ED.[SUP][10,17][/SUP] Whether BPH is associated with an increased risk of ED remains to be established.[SUP][20,21][/SUP] However, preliminary findings suggest that such an association exists and that it is independent of the expected relationship with increasing age.[SUP][20][/SUP] Moreover, in at least one study both the standard preparation of doxazosin and the gastrointestinal therapeutic system (modified release) doxazosin improved sexual function in patients with BPH.[SUP][18]


[/SUP]

 

[Nick23]

Thanks Nelson I found that odd as them saying inject 3 times a week with Trimix even if your not having. I really think HCG has to be added and is the issue an ENDO years ago did that for me and worked. Anyway spoke to Defy medical they seem first class I'm switching to them.

 

[ERO]

You need a new doctor that actually understands TRT. Call Defy Medical.

 

[Nick23]

I did ERO starting to work with them. Anyone know if HCG can cause problems if your on a blood thinner for a valve I get my INR checked regular and am good with meds.

 

[Nick23]

I got my labs back and see that my Estradiol is real high think this could be causing the problems working with defy they are suppose to schedule something this week. How long does it take to get them down and obviously high estradiol could be as bad as low t right. Seeing it can give you low libido issues also.

 

[Nelson Vergel]

What is your estradiol and your total and free T?

 

[Nick23]

Testrone 1486 upped cypionate to 400mg every 2 weeks

Free 48.9

LH .1 low

Estradiol Sensitive is 43.9 high 8.0-35.0 chart says

My cholestrol is also up never was up

 

[CoastWatcher]

As for the values you posted, it would help all of us if you could post reference ranges for test results, as you did with your estradiol scores. You are injecting 400mg of testosterone every two weeks? That is a protocol that is certainly not going to satisfy you. The half-life of testosterone doesn't lend itself to a single injection every 14 days. You are at great risk of driving your total testosterone level into supraphysiological range, and that can send your estradiol up as well. Your labs tend to suggest that is what has happened. Most of us, with the active support of our doctors, inject a smaller amount of testosterone more frequently. A good starting dose is 50mg every 3.5 days. This can stabilize your testosterone at a healthy level and minimize any estradiol spike. Good luck with your Defy consultation - I am sure you will be pleased with the result.

 

[Nick23]

Estradiol Sensitive range is suppose to be 8.0-35.0 Mine is 43.9

Basically my question is if it is that high can it cause very low libido issues? Yes I agree with you coast watcher the old endo had me doing it the old way I'll be changing with more frequent injections I agree with you your on a roller coaster every 2 weeks thanks.