hpta

TL;DR: Some research suggests that echinacoside may complement a SERM in reducing TRT-induced negative HPT-axis feedback at the hypothalamus. Background: In testosterone replacement therapy, elevated levels of testosterone and estradiol apply negative feedback to the hypothalamus. This...

When the HPTA shuts down due to mono TRT does the pituitary shut down entirely? Or does only the part that controls LH and FSH shut down?

Triptorelin is used clinically to produce castration by suppressing LH and FSH, being agonistic but constant stimulation produces the opposite effect. It has been claimed that a single dose of 100 mcg would be fine to restore HPTA. I would like to have some input on this...

Read this chapter. Chapter 12 - Hypothalamo-Pituitary Unit, Testis, and Male Accessory Organs https://www.sciencedirect.com/science/article/pii/B9780323479127000123?via%3Dihub From https://www.sciencedirect.com/book/9780323479127/yen-and-jaffes-reproductive-endocrinology

I'm attempting an HPTA restart, in the past when I used to cycle, the norm was to take Nolvadex and Clomid together. I've had pretty good success with that but I haven't done that in years. I'm seeing a lot of people suggest and clomiphene only when they decide to attempt a restart. I'm...

Hi everyone. I will be attempting to have my wife achieve pregnancy after being on TRT for long over a decade WHILE continuing to stay on TRT. I’ll be doing 50mg SQ TC shots twice a week (M-Th) while taking 300ius of HCG three times a week. I plan on doing this for 8-9 months then adding HMG...

I was on trt then got off and recovered successfully with clomid after four months. I then made the decision to get back on trt after I had fully recovered. It has been six months now and I can tell I’m still low t, and I’ve been struggling with the idea of getting on trt permanently but I...

I made a post about this on another forum, but decided to make one here too, in case someone cares haha. I quit trt on June last year, and started hcg. Was on testosterone injections for few years. I was on hcg for a bit over 6 months, and one month ago I switched it to clomid. This is all...

When I plan on discontinuing TRT and restarting my HPTA so I can get fertile. Do I need to take anything to combat gyno. I plan on 3000mg HCG three times a week with 20mg Clomid daily. I want to make sure I don’t get gyno doing this. Can anyone recommend what I should I do?

Does anyone have any experience with doing an HPTA restart while staying on Propecia? I Plan on using HCG, CLOMID, Nolvadex, HMG and was wondering if anyone was successful at achieving fertility while not discontinuing Propecia. Please no comments about dropping the Propecia. I haven’t come this...

What effects, if any, does TRT have on neurotransmitters, particularly on serotonin? I know that in the initial stages of TRT, there is a pronounced effect on dopamine - I have been told that this is what causes the "honeymoon" that many guys experience. Are there neurotransmitter imbalances...

I've been on HCG from June 15, for an attempt to restart my own testosterone production. My trt doctor prescribed a huge amount of 5000iu 2x week. I did that first, and then spared it out to 2500iu EOD after few weeks, because of the huge 5000iu dose at once seemed to give me elevated heart rate...

Admittedly the last thing we need is some other nebulous danger to worry about that may not even exist. Read on at your peril. TL;DR: Testosterone replacement therapy suppresses the production of GnRH. Receptors for GnRH are found in places besides the pituitary. One animal model suggests GnRH...

I am attempting a restart after a long and thoughtful discussion with my doc. I was advised to take pregnenolone and DHEA during the restart but I was under the impression that this would be suppressive to my HPTA? I always assumed supplementing those two were fine if on TRT, but suppressive if...

This would be after the normal 4-6 week hcg run after coming off testosterone, so would doing another run of HCG 12-16 weeks after stopping testosterone, slow the recovery process ?? I know it can take 9+months to fully recover

Hello everyone I found an article on a forum that talks about testicular desensitization, HCG and HPTA recovery. I quote you what it says. I am sure that on this forum you are experienced on the topic. "Testicular Desensitization Although steroids suppress testosterone production primarily...

Hi guys My name is Garðar and I’m from Iceland, i need advice on dr scally’s protocol. The post i was reading your comments has been locked I hope it’s ok that I post here. I’ve twice done steroid cycles and I’m prettt extreme when it comes to evertthing lol(addict but sober now 2 years) My...

I went to a urologist today and he said taking DHEA can cause one to shut down their HPTA just like testosterone can. Do you think he is right? I have heard from others that DHEA has no effect on the HPTA like testosterone does. I hope that is not the case because I have been taking DHEA for...

Long story short, I never really got "dialed-in" on TRT. My dosage fluctuated, but I never felt "great." My ending dose was 100mg test cyp (2 shots IM weekly of 50mg) and 600iu HCG (3 shots SQ weekly of 200iu), with no AI. This kept my total T at around 800 measured in my trough, and E2 at about...

Hello guys! I have read Nelson Vergel`s book,the HPTA protocol , Michael Scally PCT program as well,and there are a lot of studies about this subject! I was wondering if anyone from this forum had any success restarting HPTA?! I am trying to collect as many info as possible for next appointment...

Use of clomiphene citrate to reverse premature andropause secondary to steroid abuse Robert S. Tan, M.D., and Deepa Vasudevan, M.D. Programs in Geriatrics and Andrology, Department of Family and Community Medicine, University of Texas Health Sciences Center, Houston, Texas Objective: To...

By Dr Mauro Di Pasquale For Part 1 For Part 2 For Part 3 While there are several measures that can be taken to minimize the effects of anabolic steroids on the HPTA, perhaps the most important precaution is that the athlete take sufficient time off anabolic steroids so that the bodies...

Some men need to stop using testosterone or other androgens because side effects are a problem (e.g. low sperm count interferes with their goal to have children). Most physicians advise the patient to just stop testosterone without thinking about the possible consequences of the hypogonadal...

It Takes a While for Your Body to Start your Own Testosterone and Sperm Production Some men may want to stop testosterone replacement therapy (TRT) or anabolic androgenic steroids (AAS) due to side effects or the wish to improve fertility. We know that stopping TRT or AAS suddenly can cause...