Subcutaneous vs intramuscular testosterone study- ( abraham morgentaler )

    Sponsor- Men’s Health Boston (March 2017-March 2018)

    Summary
    In this randomized, cross‐over study 20 subjects who are undergoing testosterone (T) therapy for the treatment of T deficiency will receive both subcutaneous testosterone therapy and intramuscular testosterone therapy. One group will receive a SQ injection followed by an IM injection and one group will receive an IM injection followed by a SQ injection. The primary objective of this study is to measure testosterone concentration in men after these two treatment routes and determine if there are any significant differences due to modes of administration. Endpoints will include total serum testosterone and calculated free testosterone. A questionnaire will also be administered to assess overall patient experience with each route of administration

    Will be interesting to see results once study is completed https://www.smartpatients.com/trials/NCT03091348

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    Blackhawk

    Methodolgy seem a bit under thought out. At least what’s written is unclear. “One group will receive a SQ injection followed by an IM injection and one group will receive an IM injection followed by a SQ injection. “ So this implies basing data on single doses and not accounting for half life and reaching stable state on either method. But further in the info it states 4 weeks. It is unclear whether they are administering a single injection then measuring at weeks out which seems ludicrous, or keeping subjects on consistent dosing for 4 weeks. But then we know… Read more »

    Nelson Vergel
    Saul

    I look forward to the results of that study. IMO, it may depend a lot on the individual and their body.

    CoastWatcher

    I look forward to the results of that study. IMO, it may depend a lot on the individual and their body.

    Based simply on the anecdotal accounts we have here, I believe you’re right.

    Mando

    Any update on this trial? Can’t seem to find much info.

    Says Actual Study Completion Date : January 2, 2018