Question What are the cardiovascular risks of testosterone
replacement therapy (TRT) in men with androgen deficiency?
Findings When use in androgen-deficient men with documented
low morning testosterone levels, TRT was not associated with an
increased risk of cardiovascular outcomes. During long-term
follow-up the risk of cardiovascular outcomes was lower in
testosterone-treated men.
Meaning These findings support the use of TRT in
androgen-deficient men.
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