Low Dopamine and Testosterone Effect

Thanks for taking the time reading my post , I have an important question and couldn't find the answer by searching , ( Can Dopamine level in the brain if its low affect your feeling of TRT treatment ?

Post number two in particular.

https://www.excelmale.com/forum/showthread.php?4058-Dopamine-Prolactin-and-Sex

Thanks a lot

There are a number of us that are exploring Dopamine and other neurotransmitters and supplementing accordingly with things like Tyrosine, for one.

The article on peaktestosterone.com was very helpful for sure but still have same question What the Situation If dopamine is low and iam on TRT is that can make me feel no benefits at all from TRT ? cause i am already on TRT injection for over 70 days and literally feel nothing

Smetry said:

The article on peaktestosterone.com was very helpful for sure but still have same question What the Situation If dopamine is low and iam on TRT is that can make me feel no benefits at all from TRT ? cause i am already on TRT injection for over 70 days and literally feel nothing

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You're going to have to post labs then.

i did before but hadn't SHBG , E2 sensitive so i did the blood drown last week and still waiting for the result , Does dopamine levels have a test ?

Smetry said:

i did before but hadn't SHBG , E2 sensitive so i did the blood drown last week and still waiting for the result , Does dopamine levels have a test ?

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Post the labs from before.

Dopamine doesn't have a test.

here it is in PDF file View attachment metry.pdf

Smetry said:

here it is in PDF file View attachment 3052

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What's your protocol?

When were these taken relative to injection?

Are these fasted?

Your E2 is very low and also measured with the wrong test. It's likely AI overuse is causing you not to feel the benefits of TRT.

E2 has a connection to dopamine levels if you're curious.

My protocol for first 6 weeks 1ml T Cyp 200mg once a week + HCG 500IU twice a week + AI 0.3 mg twice a week then since i felt nothing , I changed protocol myself due to some reading to 0.5ml T Cyp and same as HCG and No AI in case thats affecting the feeling .

Test taken 2 days before following injection but the new test which iam still waiting is same day as injection but before the injection .
yes was fasting
that's not the right E2 iam waiting for the sensitive E2 and SHBG

You can stop wasting money by testing LH/FSH

Smetry said:

My protocol for first 6 weeks 1ml T Cyp 200mg once a week + HCG 500IU twice a week + AI 0.3 mg twice a week then since i felt nothing , I changed protocol myself due to some reading to 0.5ml T Cyp and same as HCG and No AI in case thats affecting the feeling .

Test taken 2 days before following injection but the new test which iam still waiting is same day as injection but before the injection .
yes was fasting
that's not the right E2 iam waiting for the sensitive E2 and SHBG

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It seems like you've done some reading and adjusted your protocol and testing methods, fire example you're testing trough now instead of 2 days before so that's good.

How long have you been on your new protocol for, before getting tests done?

I assume you've moved to 100mg E3.5D, 500IU hCG and not taking AI, correct?

no 100mg every week instead of 200mg and no AI with HCG 500iu twice a week , That's my second week on this protocol and still feel nothing

Smetry said:

no 100mg every week instead of 200mg and no AI with HCG 500iu twice a week , That's my second week on this protocol and still feel nothing

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Couple of things.

1. Testosterone and E2 take time to work. 2 weeks is nothing. It took me 2 months to notice anything and that's with perfect levels.

2. The benefits are subtle. You will not notice changes day to day or even week to week. Give it minimum 6 weeks. 8 weeks is best.

3. 100mg may be too low for you, and that's why we get labs at 6 weeks. Don't panic and increase the dose, because it may be perfect for you.

4. E2 takes time to regenerate.

5. You may honestly not notice anything yourself. People around you will notice first.

You'll be fine man, you need patience and consistency to win it in this game.

Hopefully to feel good as ppl saying all over the forums that's a great unbeatable feelings , thanks for your care

Smetry said:

Hopefully to feel good as ppl saying all over the forums that's a great unbeatable feelings , thanks for your care

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Huh? I have no idea what you're trying to say haha.

i meant all ppl on different forums saying about taking testosterone regardless its TRT or cycling its a great feeling lol sorry just wanna feel that after suffering for a years

Smetry said:

i meant all ppl on different forums saying about taking testosterone regardless its TRT or cycling its a great feeling lol sorry just wanna feel that after suffering for a years

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Read what I wrote. It's all true.

Rome wasn't built in a day. I was in exactly your position not too long ago, even called my doc's office after pulling bloods because I was angry nothing was happening at 5 weeks. 5 weeks later I'm having my follow up and it's all good! He was impressed with my improvement!

@Smetry I don't see what you're expecting to feel from TRT?

Increased Mood?
Increased Confidence?
Less indecision?
Physical strength?

Personally I did notice some physical side effects very quickly with TRT- eg strength increased, better erection quality.

The mental changes I think are very subtle and take time like JohnDoe said. After 3 months I can't attribute any specific mental feeling directly to TRT.

But the changes I've made to my habits since beginning TRT to improve my health like exercising more regularly, eating better, monitoring other health markers have put me in a much better mental state with a more positive outlook, and improved my overall confidence.

I think a lot of these things become self reinforcing - TRT might just have given me some motivation, I'm not sure.

I'm sure low dopamine levels won't leave you feeling well, TRT or not. But I think worrying about it is pointless as you can't measure it. Focus on the variables you can change and give it some time.