High DHT Concerns / Prostate?

blshaw · Nov 1, 2016

I've had some concerns regarding my DHT levels lately. I know most guys here post about DHT related to hair loss, but I could care less about that for the time being. My labs consistently show my DHT as very high, sometimes as much as 150 ng/dl with a range of 30-85 ng/dl for males. My doc has me on 50mg of progesterone a day to try and combat DHT but it just always seems to be high. My fear is that a decade or two later I am going to end up with prostate enlargement or even prostate cancer.

Anybody have any input on this? Dr Saya, you around to advise? Thanks

Vince · Nov 1, 2016

Do you supplement with vitamin K (K1,K2, mk4, mk7) my understanding is vit.K is very important prostate health.

blshaw · Nov 1, 2016

No vitamin k for me. I was mostly looking for feedback on DHT direct relationship to prostate or other issues. I've done some reading that says it's a ratio of DHT to other hormones including higher estrogens. Anybody have some in depth knowledge?

CoastWatcher · Nov 2, 2016

What was your last psa value? How often is it checked? And your age?

Vince Carter · Nov 2, 2016

CoastWatcher said:
What was your last psa value? How often is it checked? And your age?

Yes let's start there. DHT in and off itself, as you note, is NOT a prostate cancer indicator. Your DHT is curiously high but on that factor alone, I would not be concerned. Ther road you don't (my opinion) want to travel down is say Saw Palemetto, which is a known androgen blocker, and especially anything Finasteride that blocks DHT. Read up on Post-Finasteride Syndrome...it's basically chemically neutered men and they don't recover once stopped.
But as Coasty indicates if your PSA is healthy now and you have it monitored twice a year via the PSA blood test, there should be no concerns at all for prostate cancer.

Dr Justin Saya MD · Nov 2, 2016

I'll echo the above. If PSA and DRE are fine/normal/stable, then those DHT levels wouldn't present an immediate concern regarding the prostate. If those parameters change in the future, however, then the risk vs benefit would need to be re-evaluated.

blshaw · Nov 2, 2016

DRE? I get my PSA checked each blood test with no issues. I'm only 34 and secondary hypo. Mostly concerned with long term scenarios due to TRT at a youngish age. I'm located in Tampa and honestly thought about switching to Defy. How far out are you for initial consults Dr Saya?

Dr Justin Saya MD · Nov 2, 2016

blshaw said:
DRE? I get my PSA checked each blood test with no issues. I'm only 34 and secondary hypo. Mostly concerned with long term scenarios due to TRT at a youngish age. I'm located in Tampa and honestly thought about switching to Defy. How far out are you for initial consults Dr Saya?

We would welcome you. I am personally about 3-4 weeks out for initial patient consults. My PA is available sooner.

High DHT Concerns / Prostate?

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