High levels of dihydrotestosterone (DHT) may reduce diabetes risk

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Nelson Vergel

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High levels of dihydrotestosterone may reduce diabetes risk

Joyce KE, et al. J Clin Endocrinol Metab. 2016;doi:10.1210/jc.2016-2623.


Mukamal and colleagues evaluated data from the Cardiovascular Health Study on 852 men free of diabetes and cardiovascular disease in 1994 to determine the relationships between sex hormones, insulin resistance and incident diabetes.

Overall, there were 112 incident cases of diabetes. Researchers observed no statistically significant relationship between free testosterone levels and the risk for diabetes. In initial models, the risk for diabetes was 21% lower with higher dihydrotestosterone levels (P = .009), the researchers wrote.


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