Inexplicably high Estrogens

libido and interest is still very high but the ED hasn't improved, switching up using Cialis or Viagra as required, which is always. I get 50% or not hard enough, tough to maintain, the common kind of ED we see around here. Using a lot of Citrulline/Arginine/Ornithine/Carnitine/Choline with the drugs. I don't think the ED is going to be solved here with the E to be honest. Im leaning harder on NO supplementation. I had a history of a 2-3 years with stomach acid reducers like Prilosec that turns out are notorious destroyers of NO. I'm not having the heat in bed at night it's much much less and that's a good thing for me.

Vince Carter said:

I get 50% or not hard enough, tough to maintain, the common kind of ED we see around here. Im leaning harder on NO supplementation.

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Agree, I haven't been getting good pumps in the gym for some time.
I'm trying out Citrulline Malate, OKG, Pycnogenol --> around workout; Cacao powder (unprocessed), walnuts, and raw spinach leaves, and POM juice along with a baby aspirin thru the day.

The .25 Anastrozole compounded at APS - no cost difference for DIM or not DIM. Might as well.

Vince Carter said:

libido and interest is still very high but the ED hasn't improved, switching up using Cialis or Viagra as required, which is always. I get 50% or not hard enough, tough to maintain, the common kind of ED we see around here. Using a lot of Citrulline/Arginine/Ornithine/Carnitine/Choline with the drugs. I don't think the ED is going to be solved here with the E to be honest. Im leaning harder on NO supplementation. I had a history of a 2-3 years with stomach acid reducers like Prilosec that turns out are notorious destroyers of NO. I'm not having the heat in bed at night it's much much less and that's a good thing for me.

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I am following your results with high interest as I am in a similar boat and have tried most of the same things with little or no ED improvement.

I've recently been taking low doses of ipamorelin (a HGH releaser) which has done wonders for muscle growth and workout recovery time. Wonders. I'm injecting .2 ml in the morning Monday through Friday sub-q. That .2 ml contains .3 mg of ipamorelin. I've been on it about 8 weeks.

The reason I mention it is because I started noticing spontaneous partial erections 2 hours or so after some of the injections. Also began to have a few nocturnal partial erections and one that was 50%.

So the wife was in the mood yesterday afternoon and I did the usual 1 cialis + 2 viagra + the NO stack and horny goat weed and everything else - which before would only get me a bit of swelling or maybe 30%. But this time I added ipamorelin a couple hours before. What do you know we had the first penetration in at least 2 years. It lasted about 2 minutes then was gone, but she was thrilled and of course I was too. I don't know how much of a factor the ipamorelin was, but they say one of the longer term effects of increased HGH is an improvement in libido & sexual function.

I wouldn't call it a sex drug, but it may have been helpful and I will try it again the next time. Meanwhile I will look for more permanent ED solutions and will follow your results.

I messed around the those peptides and didn't like them but thanks for sharing.

Continuing on with .25mg Anast/200mg DIM EOD, about 7 weeks total now....still overly warm in the first few hours of my sleep cycle, was actually sweaty "wet" last nite. Alternately hot and cold in bed.

I have labs in two days.

28mg Cyp Daily
500iu HCG E3.5D
.25mg AI/200mg DIM, EOD
No DHEA or Pregnenlone

I started taking a DIM supplement and began acting like an ******* about absolutely trivial matters. Snapping at the wife and kids and having a really bad temper. Stopped taking it and problem was resolved. Weird.

mike7 said:

I started taking a DIM supplement and began acting like an ******* about absolutely trivial matters. Snapping at the wife and kids and having a really bad temper. Stopped taking it and problem was resolved. Weird.

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Thats the way I felt with my E so high...little things would really get my temper and it was a real challenge just keeping it in check and not unloading. Work, girlfriend, all so aggravating but I'm much better now, not totally but better. These supps and drugs all affect us so very differently.

Vince Carter said:

These supps and drugs all affect us so very differently.

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Tell me about it! After treating thousands of patients nothing surprises me anymore. I've seen just about every paradoxical reaction imaginable and have learned quite a bit from those "outlier" cases as well. It's part of the challenge, but also the beauty, of hormone treatment.

New labs:
Sensitive E down to 17 on .25mg EOD. Erection strength with 50mg Viagra is down just a little bit, as is libido down just a little bit but still pretty good. Still sexually active/able to have sex and using supplements for Nitric Oxide. (Citrulline/Arginine)
Will check on cutting the dose to 3x per week from 4x per week, perhaps M/W/F instead of EOD.

My labs came back with E2 at 27.4 ( down from 87.3). I'm using .4 Anastozole w/DIM 2x week at time of INJ (70 mg T 2X/week, hCG 500IU 2X/week day before T).

I had no idea of the power of DHEA until I tried it myself. Within a few days I blew up like a balloon. At the time, I wasn't as educated as I am now and didn't make the correlation.

The fluctuations in E2 levels are powerful

DHEA, always increases my E2

Formula364 said:

My labs came back with E2 at 27.4 ( down from 87.3). I'm using .4 Anastozole w/DIM 2x week at time of INJ (70 mg T 2X/week, hCG 500IU 2X/week day before T).

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So how are you doing at 27 now? That's dropped you right in to the ball park. I did indeed go M/W/F with my doses (.25mg/200mg DIM) and I'm doing pretty well, feel good, normal.

Vince Carter said:

So how are you doing at 27 now?

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I feel better now that the Packers sent the Giants receivers back to their boat!

Much better at 27, though I still don't feel any energy/fatigue improvement. I'll ask for a trial of desiccated thyroid during the consult at end of month. Need to give blood this week, but these are coming down, also. I was borderline high when I began TRT mid-September:

Hemoglobin 18.4 (12.6 - 17.7)
Hematocrit 54.4 (37.5 - 51.0)

Formula364 said:

I feel better now that the Packers sent the Giants receivers back to their boat!

Much better at 27, though I still don't feel any energy/fatigue improvement. I'll ask for a trial of desiccated thyroid during the consult at end of month. Need to give blood this week, but these are coming down, also. I was borderline high when I began TRT mid-September:

Hemoglobin 18.4 (12.6 - 17.7)
Hematocrit 54.4 (37.5 - 51.0)

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That's not borderline high especially if that was in september.

Before TRT it was 16.5 and 48.5. When E2 was 87.2 before Anastrozole (11/4) they were 19.1 and 54.5!
Both Vince C. and I have good E2 reduction, now.

One thing I never really considered in all this and I've moved on to Free Estrogens (low SHBG = very high Free T = very high Free E) was a Cyp dose reduction, bringing my Free T way down. Im currently experimenting with AI @ appx .35mg EOD. Maybe I should have cut the Cyp dose down instead of upping the AI.

Cyp/D 28mg
HCG 100iu 2xW
.25mg EOD

5 Jan
TT 1322 (strange because just a few months ago I pulled a 922 on the same dose)
Free T 439 (35-155)
LC/MS/MS 42
Estrogen, Free 0.91 (<=.45)
Estrogen 35 (<=29)

New numbers:

TT 1072 (250-1100) (blood was drawn @ 0815 appx 27hrs post injection as I normally injection at 5am daily)
FT 293 (35-155)
LC/MS/MS 46

This was a reduction in my Cyp dose of 4mg per day from 28mg > 24mg/D, using .25mg AI EOD which was taken that morning 2hrs before bloods.

Still sweaty at night like blankets/pillow with some moisture, seems I'm on a flux of either being slightly sweaty or just too warm I pass back and forth from night to night.

What I can do is further cut Cyp to 20mg/D,

or

.5mg AI E3D

Vince Carter said:

New numbers:

TT 1072 (250-1100) (blood was drawn @ 0815 appx 27hrs post injection as I normally injection at 5am daily)
FT 293 (35-155)
LC/MS/MS 46

This was a reduction in my Cyp dose of 4mg per day from 28mg > 24mg/D, using .25mg AI EOD which was taken that morning 2hrs before bloods.

Still sweaty at night like blankets/pillow with some moisture, seems I'm on a flux of either being slightly sweaty or just too warm I pass back and forth from night to night.

What I can do is further cut Cyp to 20mg/D,

or

.5mg AI E3D

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I would further cut the cyp.

Dr Saya Im going to do that I'm not keen on more AI, I'm fine using what I'm am right now but the prospect of needing more isn't desirable. I'll start 20mg/D on Thurs this.