Lab Results Before my First Consultation with Defy Medical...Thoughts Please......

Im 41 African American(if that matters?) work out 4xweek. Been having tons of sympotoms. Im scheduled for Dr Crisler June 30(your thoughts on that as well)Dr Saya was booked to far out everyone here seems to praise him a lot..From my readings i see about 4 red flags Hematocrit,ldl,estradol,luetinizing harmones, now what that means not for sure




CBC With Differential/Platelet
WBC 6.7 3.4 - 10.8 01
RBC 5.05 4.14 - 5.80 01
Hemoglobin 15.8 12.6 - 17.7 01
Hematocrit 47.9 37.5 - 51.0 01
MCV 95 79 - 97 01
MCH 31.3 26.6 - 33.0 01
MCHC 33.0 31.5 - 35.7 01
RDW 13.8 12.3 - 15.4 01
Platelets 198 150 - 379 01
Neutrophils 56
Lymphs 36
Monocytes 6
Eos 1
Basos 1
Neutrophils (Absolute) 3.7 1.4 - 7.0 01
Lymphs (Absolute) 2.4 0.7 - 3.1 01
Monocytes(Absolute) 0.4 0.1 - 0.9 01
Eos (Absolute) 0.1 0.0 - 0.4 01
Baso (Absolute) 0.1 0.0 - 0.2 01
Immature Granulocytes 0
Immature Grans (Abs) 0.1 0.0 - 0.1 01
Comp. Metabolic Panel (14)
Glucose, Serum 95 65 - 99 01
BUN 15 6 - 24 01
Creatinine, Serum 1.24 0.76 - 1.27 01
eGFR If NonAfricn Am 71 >59
eGFR If Africn Am 82 >59

BUN/Creatinine Ratio 12 9 - 20
Sodium, Serum 139 134 - 144 01
Potassium, Serum 4.1 3.5 - 5.2 01
Chloride, Serum 102 97 - 108 01
Carbon Dioxide, Total 24 18 - 29 01
Calcium, Serum 9.0 8.7 - 10.2 01
Protein, Total, Serum 7.6 6.0 - 8.5 01
Albumin, Serum 3.9 3.5 - 5.5 01
Globulin, Total 3.7 1.5 - 4.5
A/G Ratio 1.1 1.1 - 2.5
Bilirubin, Total 0.8 0.0 - 1.2 01
Alkaline Phosphatase, S 66 39 - 117 01
AST (SGOT) 28 0 - 40 01
ALT (SGPT) 40 0 - 44 01
Lipid Panel w/ Chol/HDL Ratio
Cholesterol, Total 157 100 - 199 01
Triglycerides 54 0 - 149 01
HDL Cholesterol 44 >39 01
VLDL Cholesterol Cal 11 5 - 40
LDL Cholesterol Calc 102 0 - 99
T. Chol/HDL Ratio 3.6 ratio units 0.0 - 5.0
Testosterone,Free and Total Testosterone, Serum 461 ng/dL 348 - 1197 01 Comment: Adult male reference interval is based on a population of lean males up to 40 years old.
Free Testosterone(Direct) 9.7 6.8 - 21.5 02
DHEA-Sulfate 272.1 102.6 - 416.3 01
TSH 1.760 0.450 - 4.500 01
Luteinizing Hormone(LH), S LH 10.4 High mIU/mL 1.7 - 8.6 01

INTERVAL LAB
Prostate-Specific Ag, Serum Prostate Specific Ag, Serum 0.7 ng/mL 0.0 - 4.0 01 Roche ECLIA methodology. According to the American Urological Association, Serum PSA should decrease and remain at undetectable levels after radical prostatectomy. The AUA defines biochemical recurrence as an initial PSA value 0.2 ng/mL or greater followed by a subsequent confirmatory PSA value 0.2 ng/mL or greater. Values obtained with different assay methods or kits cannot be used interchangeably. Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.
Estradiol, Sensitive 45.5 High pg/mL 8.0 - 35.0 02
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared by the Food and Drug Administration. Methodology: Liquid chromatography tandem mass spectrometry(LC/MS/MS)
Progesterone 0.7 ng/mL 0.2 - 1.

busa2009 said:

Im 41 African American(if that matters?) work out 4xweek. Been having tons of sympotoms. Im scheduled for Dr Crisler June 30(your thoughts on that as well)Dr Saya was booked to far out everyone here seems to praise him a lot..From my readings i see about 4 red flags Hematocrit,ldl,estradol,luetinizing harmones, now what that means not for sure

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Did you get SHBG and FSH tested? I didn't see it on your results. It would have been nice to have a more comprehensive thyroid panel also...but your TSH looks good.

As for your HCT and LDL, you're fine. You're going to need to monitor your HCT, Hemoglobin, and RBCs (like all of us) once you start TRT. Your total and free testosterone definitely have room for improvement. Your LH will go to zero after you've been on TRT for a while...this is normal.

Your sensitive E2 is a little high, but that can be managed when you start TRT. What symptoms are you having? Your low test level combined with your slightly elevated E2 level probably aren't helping you. Your DHEA(S) can be easily raised into the high end of the range.

You're in great hands with Dr. Crisler.

Jackie Treehorn said:

Did you get SHBG and FSH tested? I didn't see it on your results. It would have been nice to have a more comprehensive thyroid panel also...but your TSH looks good.

As for your HCT and LDL, you're fine. You're going to need to monitor your HCT, Hemoglobin, and RBCs (like all of us) once you start TRT. Your total and free testosterone definitely have room for improvement. Your LH will go to zero after you've been on TRT for a while...this is normal.

Your sensitive E2 is a little high, but that can be managed when you start TRT. What symptoms are you having? Your low test level combined with your slightly elevated E2 level probably aren't helping you. Your DHEA(S) can be easily raised into the high end of the range.

You're in great hands with Dr. Crisler.

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Im def having cycles of mood changes( not for sure if its depression) but def can admit finally having some mood changes
Im def seeing a big pattern in sleep as well, also fighting like hell to keep active in the gym even though i love going but its getting harder..My libido has def taking a dive for the worse fighting that in itself can cause some mood issues....
Memory not that good here lately as well, energy im sure thats tied to my mood...I try and do focus wheel type shit to stay motivated and focused, but that only goes so far....My attention span sucks like hell as well...recovery from workouts is def longer...Im still at a stand still as to how im able to keep on so much muscle...I never tried steroids or prohormones either... Hardest part for me though is admitting that i have mood changes that may very well be depression..ugh.....grumpy alot guess thats mood change as well...Energy has went down tremendously as well...

Im assuming muscle and low t dont go hand in hand...guess thats why i was so reluctant to get tested...Glad i man up and got it done because i learn more about my blood work as well with this site...

busa2009 said:

Im assuming muscle and low t dont go hand in hand...guess thats why i was so reluctant to get tested...Glad i man up and got it done because i learn more about my blood work as well with this site...

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Busa,

You're definitely doing the right thing. Lots of guys out there just accept it as the "normal aging process," and are miserable. Lots of uninformed doctors out there call it normal aging process too. Not the case with Drs. Crisler or Saya. They understand the importance of optimizing your hormone levels, so you can feel your best, and live your life to the fullest.

All of the symptoms you listed are classic low T symptoms. Another test you may want to look into is a Cortisol Saliva test. Saliva samples are taken at 4 different times in a day (Midnight, 8am, 4pm, 8pm). High cortisol levels at bedtime will adversely affect your sleep. They can also affect sex drive and mood. This too can be treated.

Good luck with your consult. Dr. Crisler will take good care of you.

You have all the classic symptoms that accompany low testosterone - including a degree of doubt and anxiety as to how in the world you wound up here. The good news is that you are scheduled to consult with one of the leading androgen specialists in North America; you have every reason to be hopeful.

A question: you are only 41. Is maintaining fertility an issue?

Jackie Treehorn said:

Busa,

You're definitely doing the right thing. Lots of guys out there just accept it as the "normal aging process," and are miserable. Lots of uninformed doctors out there call it normal aging process too. Not the case with Drs. Crisler or Saya. They understand the importance of optimizing your hormone levels, so you can feel your best, and live your life to the fullest.

All of the symptoms you listed are classic low T symptoms. Another test you may want to look into is a Cortisol Saliva test. Saliva samples are taken at 4 different times in a day (Midnight, 8am, 4pm, 8pm). High cortisol levels at bedtime will adversely affect your sleep. They can also affect sex drive and mood. This too can be treated.

Good luck with your consult. Dr. Crisler will take good care of you.

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I will def look into the cortisol test as well, and thank you for the information.

CoastWatcher said:

You have all the classic symptoms that accompany low testosterone - including a degree of doubt and anxiety as to how in the world you wound up here. The good news is that you are scheduled to consult with one of the leading androgen specialists in North America; you have every reason to be hopeful.

A question: you are only 41. Is maintaining fertility an issue?

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Well I been really thinking hard on that subject and I'm honestly wanting to keep that option very open because you never know. If I wanted to keep that option open what would be the best route or starting point?

Inclusion of HCG is in lockstep with TCyp by Defy Medical. You'll needn't dwell on fertility, per se, but keeping the testes alive is important for other hormonal pathways that exist there and then inducing organ failure is just not a smart thing to do. Many men experience pain as the testes atrophy, and die, then there's the outward cosmetic appearance of a grown man with tiny shrunken nuts.

LIke you about half my initial symptoms I found in the gym, effort was not translating to results, weight gain (fat), long(er) recovery times, strength and size diminished, it was very frustrating. But we reversed all that with therapy and my gym life has taken off remarkably the last 18 months.

Welcome to the forum!

Trying to "re-start" or improve your HTPS axis response with Clomid would be a possible option before going on Testosterone replacement. That, if it works, basically gets your body to produce more Testosterone itself so fertility is maintained. Its not necessarily a fun ride though as a lot of guys do not feel great while on Clomid.

Alternatively, a TRT protocol with HCG (as you would have with Dr. Crisler) keeps your testes from atrophying so future fertility is not ruled out. Be sure to write up a list of questions to ask during your initial consult as well - its easy to forget a question or two if you don't have a list.

ERO said:

Welcome to the forum!

Trying to "re-start" or improve your HTPS axis response with Clomid would be a possible option before going on Testosterone replacement. That, if it works, basically gets your body to produce more Testosterone itself so fertility is maintained. Its not necessarily a fun ride though as a lot of guys do not feel great while on Clomid.

Alternatively, a TRT protocol with HCG (as you would have with Dr. Crisler) keeps your testes from atrophying so future fertility is not ruled out. Be sure to write up a list of questions to ask during your initial consult as well - its easy to forget a question or two if you don't have a list.

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thanks, thats what im nervous about as well, leaving the consultation then remembering things i should have asked..What are some of the common questions people tend to forget to address in your opinion?

The consults with Defy are great as the Doctors take their time and are happy to answer all your question without rushing you - its just that IMHO you are going over a lot of information all at once and so it is easy complete the consult and then realize you had a question or two that you totally forgot to ask. Remember too that there are no dumb questions - so I would just start a list now of any questions you have and then you can have that list handy when your consult comes up. In your case ask some questions about a Clomid re-start, ask about go-forward fertility, ask about brain fog, etc.

You are in great hands with Defy Medical - starting out with a great TRT doc is going to save you the months of grief that many of us had when we started TRT with an uninformed Doc.

The Defy staff is always avail for simple questions and answers, whether on this forum, or via email and telephone, you needn't worry to much. Questions usually center around what aspects matter the most to you, or are the most bothersome, you're most pressing issues. The first consult is just a jumping off point to get you started, it's 6 weeks and 90 days later that you get another consult and start working on residual issues that haven't resolved or improved to that point.

Luteinizing Hormone(LH), S LH 10.4 High mIU/mL 1.7 - 8.6 01 you look like primary(balls) hypogonadism to me I don't know if clomid would work for you but it wouldn't hurt to ask HCG will help keep your fertility and testical size.
your estrogen is high for your testosterone levels IMO do you have sensitive nipples?
cholesterol and everything besides testosterone levels look good to me.
Good luck keep us updated on how thing go!

PAUL-E said:

Luteinizing Hormone(LH), S LH 10.4 High mIU/mL 1.7 - 8.6 01 you look like primary(balls) hypogonadism to me I don't know if clomid would work for you but it wouldn't hurt to ask HCG will help keep your fertility and testical size.
your estrogen is high for your testosterone levels IMO do you have sensitive nipples?
cholesterol and everything besides testosterone levels look good to me.
Good luck keep us updated on how thing go!

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Hmmm, wow Im learning so much on this site...Come to think of it yes i would consider i have sensitive nipples hell thought it was normal..lol...oh well...Is that a sign or symptom of something bad if so what?

busa2009 said:

Hmmm, wow Im learning so much on this site...Come to think of it yes i would consider i have sensitive nipples hell thought it was normal..lol...oh well...Is that a sign or symptom of something bad if so what?

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sensitive nipples sometimes = high estrogen, for some can be a early warning sign for gyno

PAUL-E said:

sensitive nipples sometimes = high estrogen, for some can be a early warning sign for gyno

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guess that would be good to put on my to address list when I talk with them on the 30th...One questions though off topic...After the consultation will they go to the drawing board and get back with me on a plan or will that be ironed out as we converse?

busa2009 said:

guess that would be good to put on my to address list when I talk with them on the 30th...One questions though off topic...After the consultation will they go to the drawing board and get back with me on a plan or will that be ironed out as we converse?

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They will go over lab work with you explain things and answer questions then go over protocol during your consultation. They have a friendly staff you can also call them and ask the any questions as far as process as well.