Evidence review places benefits, drawbacks of testosterone therapy in context for physicians
Testosterone replacement remains controversial due to a shortage of large clinical trials demonstrating the benefits and adverse effects of treatment in boys and men of all ages. However, available evidence and published clinical experience may help physicians determine for whom this therapy is appropriate.“Treatment of testosterone deficiency due to classical diseases affecting the hypothalamus, pituitary and/or testes has been accepted for decades, although there were no multicenter trials,”Glenn R. Cunningham, MD, and Shivani M. Toma, MD, both of the Baylor College of Medicine and St. Luke’s Episcopal Hospital in Houston, wrote in a recent review. |