Effect of Blood Pressure Medications on erections

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The Effect of Antihypertensive Drugs on Erectile Function: A Proposed Management Algorithm - By Michael Doumas MD, Stella Douma

Blood pressure medications are among the most common causes of drug-induced decrease in sex drive and erectile function. This great paper reviews known data on the subject.


Blood pressure medications are one of the main culprits of erectile dysfunction in men who are aging. This is a great review of medications and algorithms. Too bad that it does not include the use of testosterone in that algorithm!


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Nelson Vergel

Founder, ExcelMale.com
The Effect of Antihypertensive Drugs on Erectile Function: A Proposed Management Algorithm


Older-generation antihypertensive drugs (central-actin, blockers, diuretics) negatively affect erectile function, while newer-generation agents (calcium antagonists and ACE inhibitors) seem to have neutral effects, and ARBs exhibit a beneficial effect on erectile function. However, available data cannot be characterized as of high quality since they are mostly derived either from open studies or by using inappropriate assessment methods. Thus, accurate studies (double-blind, using appropriate inventories) are needed to clarify these unresolved issues.
 
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Nelson, can doxazosin have a negative effect on elections? I thought that alpha blocker was OK for erection....it can actually help. It's part of genes no stack!
 

Nelson Vergel

Founder, ExcelMale.com
No, doxazosin is an alpha blocker that actually improves erectile function. Just be careful since it can lower blood pressure too much when used with Viagra. It can also cause fatigue in some men.

Combined oral therapy with sildenafil and doxazosin for the treament of non-organic erectile dysfunction refractory to sildenafil monotherapy

A F De Rose1, M Giglio1, P Traverso1, P Lantieri2 and G Carmignani1

1Department of Urology, S. Martino Hospital, University of Genoa, Italy

2Department of Medical Statistics, S. Martino Hospital, University of Genoa, Italy


Abstract

The purpose of this work was to investigate the efficacy and safety of sildenafil in combination with doxazosin for the treatment of non-organic erectile dysfunction in patients who did not respond to sildenafil. We enrolled 28 patients with non-organic erectile dysfunction, for whom 3 months of sildenafil monotherapy had failed. They were divided in two random and homogeneous groups: 14 were treated with doxazosin (4 mg daily) and sildenafil (100 mg 1 h before sexual intercourse); the other 14 patients received sildenafil and placebo. The results were assessed by means of the IIEF questionnaire before the beginning of the study, after 30 days of therapy and after 60 days. Of the 14 patients treated with doxazosin and sildenafil, 11 (78.6%) showed a statistically significant increase of IIEF; in the placebo group, only one patient (7.1%) recorded a significant IIEF increase. The differences observed in the two groups were statistically very significant (P=0.0016). Blood pressure did not show significant alterations. Side effects were minimal and even present during sildenafil monotherapy. The combination therapy with sildenafil and doxazosin resulted in the safe and effective treatment of men with non-organic erectile dysfunction for whom sildenafil alone had failed.

International Journal of Impotence Research (2002) 14, 50-53. DOI: 10.1038/sj/ijir/3900815
 

joshmaximus

Member
No, doxazosin is an alpha blocker that actually improves erectile function. Just be careful since it can lower blood pressure too much when used with Viagra. It can also cause fatigue in some men.

Combined oral therapy with sildenafil and doxazosin for the treament of non-organic erectile dysfunction refractory to sildenafil monotherapy

A F De Rose1, M Giglio1, P Traverso1, P Lantieri2 and G Carmignani1

1Department of Urology, S. Martino Hospital, University of Genoa, Italy

2Department of Medical Statistics, S. Martino Hospital, University of Genoa, Italy


Abstract

The purpose of this work was to investigate the efficacy and safety of sildenafil in combination with doxazosin for the treatment of non-organic erectile dysfunction in patients who did not respond to sildenafil. We enrolled 28 patients with non-organic erectile dysfunction, for whom 3 months of sildenafil monotherapy had failed. They were divided in two random and homogeneous groups: 14 were treated with doxazosin (4 mg daily) and sildenafil (100 mg 1 h before sexual intercourse); the other 14 patients received sildenafil and placebo. The results were assessed by means of the IIEF questionnaire before the beginning of the study, after 30 days of therapy and after 60 days. Of the 14 patients treated with doxazosin and sildenafil, 11 (78.6%) showed a statistically significant increase of IIEF; in the placebo group, only one patient (7.1%) recorded a significant IIEF increase. The differences observed in the two groups were statistically very significant (P=0.0016). Blood pressure did not show significant alterations. Side effects were minimal and even present during sildenafil monotherapy. The combination therapy with sildenafil and doxazosin resulted in the safe and effective treatment of men with non-organic erectile dysfunction for whom sildenafil alone had failed.

International Journal of Impotence Research (2002) 14, 50-53. DOI: 10.1038/sj/ijir/3900815
Have u heard of Terazosin or prazosin better than doxazosin?
 
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