Does anyone use Nandrolone (Deca Durabolin) ?

MAD King said:

With only one phlebotomy therapy? wow.

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Yes. I know. It is probably due to not having a very active bone marrow after years of HIV. I also think my red blood cells started changing shape to compensate, as shown in an animal study below.

Hematocrit may stabilize after long term testosterone replacement

Although this study was done in mice, it may explain why hematocrit may eventually decrease and stabilize in men on TRT. I am one of those men who only went for therapeutic phlebotomy twice. There seems to be an adaptive mechanism that makes red blood cells get change form while hematocrit stabilizes.

Guo W, Bachman E, Vogel J, Li M, Peng L, et al. The Effects of Short-Term and Long-Term Testosterone Supplementation on Blood Viscosity and Erythrocyte Deformability in Healthy Adult Mice. Endocrinology.http://press.endocrine.org/doi/abs/10.1210/en.2014-1784


Testosterone treatment induces erythrocytosis that could potentially affect blood viscosity and cardiovascular risk. We thus investigated the effects of testosterone administration on blood viscosity and erythrocyte deformability using mouse models.


Blood viscosity, erythrocyte deformability, and hematocrits were measured in normal male and female mice, as well as in females and castrated males after short-term (2-weeks) and long-term (5-7 months) testosterone intervention (50 mg/kg, weekly).


Castrated males for long-term intervention were studied in parallel with the normal males to assess the effect of long-term testosterone deprivation. An additional short-term intervention study was conducted in females with a lower testosterone dose (5 mg/kg).


Our results indicate no rheological difference among normal males, females, and castrated males at steady-state.


Short-term high dose testosterone increased hematocrit and whole blood viscosity in both females and castrated males. This effect diminished after long-term treatment, in association with increased erythrocyte deformability in the testosterone-treated mice, suggesting the presence of adaptive mechanism.


Considering that cardiovascular events in human trials are seen early after intervention, rheological changes as potential mediator of vascular events warrant further investigation.


Definition of Erythrocyte deformability


I have seen how in some men red blood cell indices (MCV and MCHC) start changing after starting TRT as a way for the body to compensate for the extra production of red blood cells.

Red blood cell indices: There are three red blood cell indices: mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). They are measured by a machine, and their values come from other measurements in a CBC. The MCV shows the size of the red blood cells. The MCH value is the amount of hemoglobin in an average red blood cell. The MCHC measures the concentration of hemoglobin in an average red blood cell. These numbers help in the diagnosis of different types of anemia. Red cell distribution width (RDW) can also be measured which shows if the cells are all the same or different sizes or shapes.

Than you Nelson. I will do a blood test after three sessions of this therapy and compare my previous levels with it. I hope is also stabilizes in my case.

I wonder if this is true. I have been taking this drug for BP for the past 2 years but I can't tell since I have not had high hematocrit for years. Anyone?

Can Losartan decrease high hematocrit caused by testosterone replacement?

Hey Paul E,

Why you on cialis etc?

Nick said:

Hey Paul E,

Why you on cialis etc?

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Speaking not for PAUL-E, but for many, many members of our community, I can assure you that Cialis is a part of our protocol because erectile dysfunction is multi-faceted and TRT is frequently not, in and of itself, enough to resolve the question. There are also multiple studies indicating that Cialis is a remarkable drug that men should evaluate for its anti-aging properties.

I wish my doc would prescribe deca. Have always liked deca with test, felt great, strong, no aches/pains. Oh and no sides.

I don't have a wasting disease, but I'm wasting and my joints are getting worse " wasting ".

Nick said:

Hey Paul E,

Why you on cialis etc?

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https://www.excelmale.com/forum/showthread.php?7651-Tadalafil(Cialis)-how-long-to-kick-in

maxadvance said:

No negative effect on libido, in fact it got better.

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I'm noticing this as well

Well 2 years ago i did 500mg of test and 100mg of deca gained 8kgs but hold a lot of water retention for sure thats why my BP was a little high and after some weeks i did bw and prolactin was very high, so for me high prolactin on deca its not a myth. At that time did some caber (cant remember the protocol) and than it came normal after a month or so after caber.

My question is since i have prolactin probs with deca which dose should i use weekly or daily to maintain the levels ok?

Final question epstein barr is back on my system, immune system is weak should i do this anyway or take some time?

Very good read. I've been reading other places saying that even 50-75mg of Deca a Week can show joint pain relief. Anybody run that low of a dose?

PAUL-E said:

I have a previous prolactin and progesterone tests(on TRT but no HCG). I'm planning on testing them both at the end of August I will post the results without nandrolone and with nandrolone. I have to say I'm happy with my libido and my new protocol.

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My progesterone did not increase it went from .7(pre Nandrolone) to .1(post Nandrolone) I don't have my last prolactin tests but no issues there as well and I'm confident its not any higher than before. My experience with therapeutic Nandrolone has been positive way WAY better than vicodin, Percocet, ect. with no negative side effects its a real shame the FDA/DEA Nazi's are they way they are when it comes to this and similar medications.

was the deca for health reasons, or as part of a cycle? if the former what was the issue and how did it work

MikeXL said:

was the deca for health reasons, or as part of a cycle? if the former what was the issue and how did it work

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https://www.excelmale.com/forum/showthread.php?6554-Nandrolone-for-CRPS-RSD

Also has helped past neck and back issues that I just kind of learned to live with.

I find out that nandrolone 250mg/week increase my sex drive and livido to the roof, I need sex every day.
I been with nandrolone for 4 weeks, this feeling will last ?
will I feel bad when I stop nandrolone ? my plan is 8 weeks.
Should I increase testo when I stop nandrolone ?

I'm with testo 60 mg + HCG 300ui each 3,5 days.

Deca Heals Bone Fractures

How many of us have fractured a bone at one point in our lives? From climbing trees as children, to playing contact sports, to simple falls or accidents, it happens to many of us. We often don't think of fractures as much more than a temporary nuisance, but they can be very serious injuries. The healing of a fractured bone is a complex process that involves several stages. First, the injured area has an inflammatory reaction. Next, a callus forms at the fracture. Finally, the callus and bone are remodeled, hopefully restoring its original shape and strength. Often this healing process is not complete, however. This risk increases in the elderly, with patients often noticing secondary weight loss, impaired mobility and loss of function. This has many in the medical field searching for new therapies to support fracture healing. As it turns out, one of the most effective may actually not be new at all, but our ages-old anabolic steroids.



A paper recently published in the Journal of Clinical and Diagnostic Research examined the effect of Deca-Durabolin (nandrolone decanoate) on fracture healing.1 The experiments involved rabbits, which were anesthetized and then given fractures. In groups that were also given nandrolone decanoate, fracture healing was significantly more pronounced. This was characterized in part by higher levels of callus formation. Osteoblastic activity, as measured by local alkaline phosphatase concentrations, was also significantly more pronounced. Bone catabolic activity, a process known as bone resorption, was also reduced. Looking at the fracture points in the animals, the calluses were denser when they were given nandrolone, and the gaps better healed. The researchers were left to conclude that anabolic steroids such as nandrolone could not only help heal bone fractures, but possibly improve the overall negative health and socio-economic impact of such injuries. I can't help but agree.

http://musculardevelopment.com/arti...ates-on-growth-hormone-deca.html#.WEmLjdXR8Wr

Nelson Vergel said:

Great question.

LDL management is easy: diet and exercise (and my lucky genes). I never had to take a statin.


HDL- Super hard. Niacin improves it by10% at most if you can tolerate it. I tried all of these supplements but my HDL remained in the 28-32 range.

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If your cholesterol levels are low, you probably don't need a lot of HDL anyway.

Jonny said:

Well 2 years ago i did 500mg of test and 100mg of deca gained 8kgs but hold a lot of water retention for sure thats why my BP was a little high and after some weeks i did bw and prolactin was very high, so for me high prolactin on deca its not a myth. At that time did some caber (cant remember the protocol) and than it came normal after a month or so after caber.

My question is since i have prolactin probs with deca which dose should i use weekly or daily to maintain the levels ok?

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According to what I've read, Vitamin B6 lowers prolactin levels. It's best if you use a form of Vitamin B6 commonly called "P5P".

Are you guys actually able to get a script for Deca? I would love to give it a try for back pain, tendonitis. Didn't even think of asking my Dr but I seriously doubt he would.

drpepper68 said:

Are you guys actually able to get a script for Deca? I would love to give it a try for back pain, tendonitis. Didn't even think of asking my Dr but I seriously doubt he would.

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Yes, I am able to get a script from my physician, and I don't have a wasting disease. I do have plenty of pain, however, and I have never noticed any benefit whatsoever from nandrolone.

The notion that nandrolone is good for treating pain seems to be more "bro science" than real science.

I am a PT. I have been educating myself on nandrolone deconate for the past few months b/c I am interested in doing a cycle of it for muscle composition. But I too come across study after study like this one. I swear if I needed orthopedic surgery i would pretty much demand 100-200mg a week to facilitate proper healing. Even post injury until the surgery could take place. I think of so very many patients that could have benefited from this. Low dose does the trick and the side effects are minimal.