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Component Results
Component Standard Range

Testosterone 789 348 - 1197 ng/dL
Testosterone, free 24.22. 5.00 - 21.00 ng/dL
% Free testosterone 3.07 1.50 - 4.20
Estrogens,total 239 40 - 115 pg/mL
TSH 4.430 0.450 - 4.500 uIU/mL
Glucose 71 65 - 99 mg/dL
BUN. 12 6 - 20 mg/dL
Creatinine 0.94 0.76 - 1.27 mg/dL
GFR est non-AA 106 >59 mL/min/1.73
GFR est AA 123. >59 mL/min/1.73
BUN/Creatinine ratio 13 8 - 19
Sodium 141 134 - 144 mmol/L
Potassium 4.5 3.5 - 5.2 mmol/L
Chloride 102 97 - 108 mmol/L
CO2 25 18 - 29 mmol/L
Calcium 10.1 8.7 - 10.2 mg/dL
Protein, total 7.0 6.0 - 8.5 g/dL
Albumin 4.8 3.5 - 5.5 g/dL
GLOBULIN, TOTAL 2.2. 1.5 - 4.5 g/dL
A-G Ratio. 2.2 1.1 - 2.5
Bilirubin, total 0.6. 0.0 - 1.2 mg/dL
Alk. phosphatase 73 39 - 117 IU/L
AST 0 - 40 IU/L 38
ALT 0 - 44 IU/L 58
Cholesterol, total 100 - 199 mg/dL 185

Triglyceride 0 - 149 mg/dL 283
HDL Cholesterol >39 mg/dL 27
VLDL, calculated 5 - 40 mg/dL 57
LDL, calculated. 0 - 99 mg/dL 101
WBC 3.4 - 10.8 x10E3/uL 10.6
RBC 4.14 - 5.80 x10E6/uL 5.53
HGB 12.6 - 17.7 g/dL 16.0
HCT 37.5 - 51.0 % 46.9
MCV 79 - 97 fL 85
MCH 26.6 - 33.0 pg 28.9
MCHC 31.5 - 35.7 g/dL 34.1
RDW 12.3 - 15.4 % 14.3
PLATELET 150 - 379 x10E3/uL 323
NEUTROPHILS 40 - 74 % 58
Lymphocytes 14 - 46 % 30
MONOCYTES 4 - 12 % 8
EOSINOPHILS 0 - 5 %. 4
BASOPHILS 0 - 3 % 0
ABS. NEUTROPHILS 1.4 - 7.0 x10E3/uL 5.9
Abs Lymphocytes 0.7 - 3.1 x10E3/uL 3.2
ABS. MONOCYTES 0.1 - 0.9 x10E3/uL 0.9
ABS. EOSINOPHILS 0.0 - 0.4 x10E3/uL 0.5
ABS. BASOPHILS 0.0 - 0.2 x10E3/uL 0.0
IMMATURE GRANULOCYTES 0 - 2 % 0
ABS. IMM. GRANS. 0.0 - 0.1 x10E3/uL 0.0


I have reviewed your lab results. They show :

Triglycerides improved, but still elevated
Stable increase in liver enzyme
Thyroid normal
Testosterone above goal of 500-600, please follow up with endocrinology.
 
Defy Medical TRT clinic doctor

Gene Devine

Super Moderator
What is your testosterone replacement protocol?

Your estrogen level, even using the standard default lab and not the "sensitive" lab designed for men, is through the roof and in a dangerous level. I am surprised you are not complaining about of negative side effects of such a level.

You need to get this down into the 20's with the use of an aromatase inhibitor as soon as you can.

Your TSH levels are elevated and is an indication that your Thyroid is not okay and would require further testing. Any TSH value over 3 is clear sign to a knowledgeable physician that further Thyroid testing needs to be done. Reference ranges for TSH are not normal.

HCT which I believe is short for Hematocrit would be fine here.

Clearly someone doesn't know how to manage your correctly IMO.

Tell us more about yourself and our protocol please.

Gene
 
I am 33, 270 pounds, 6'. I've been on TRT for just over a year. My current injection dosage is 150mg/every 7 days. I asked about an AI at my last check up. The Dr. Wanted to see where these labs came in and go from
there. This is the first time my E has come back out of the normal range. To be honest I'm not sure what the negative side effects would be. The last few weeks, my body and joints ache much worse than when they did even prior to starting TRT. The last few days Ive had several dizzy spells, and feel "shaky" at times. I do not know if any or all of this has anything to do with my high Estrogen levels
 

Vettester Chris

Super Moderator
You need additional labs Free T3/T4 Reverse & TPO/TgAb antibodies. Good chance you're dealing with the same thyroid issues that your sister has. Maybe she could provide you with some details regarding her diagnosis, which could help as you explore this further.

Other labs that would also compliment this would be: iron serum, TIBC, iron sat, magnesium, & a 4x saliva cortisol panel could be quite useful when looking at the whole spectrum of this.
 
I talked to my Drs nurse yesterday. Initially I was told that the Dr. seemed unconcerned. I expressed to the nurse that this bothered me and she scheduled an appointment to discuss "alternative solutions". What other solution is there for high estrogen?
 

Vettester Chris

Super Moderator
The "solution" to high estrogen is to manage it with an AI (e.g., Anastrozole), and/or adjust exogenous testosterone to where you don't see a series of peaks that spikes to where E2 conversion isn't as problematic.

Take your 150mg/week and go with 75mg/2x per week, administered SubQ, and that will stabilize serum levels a little better, and will/should curb the estrogen conversion a bit. At 6'-0" and 277lbs, you are either stacked like Jay Cutler, or you need to reduce your body fat. If it's the later, then estrogen can be a bit more problematic than if you were say 210lbs. It's not a knock or anything, it's just the nature of how this works.

Sometimes with TRT, there's just no way around it but to implement a small amount of AI. Again, it's just the nature of the beast with hormones ... Testosterone converts downstream into the 3 different profiles of occurring estrogen, that's just part of the precursor flow chart in the endocrine system.
 
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