1. #1
    Super Moderator Nelson Vergel's Avatar
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    Sep 2013
    Houston, Texas, United States

    How long does testosterone take to show effects?

    A review of studies attempted to determine the time-course of the effects induced by testosterone replacement therapy from their first manifestation until maximum effects are attained.

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    This review found that:

    · Effects on sexual interest appear after 3 weeks plateauing at 6 weeks, no further increments beyond.

    · Changes in erections/ejaculations may require up to 6 months.

    · Effects on quality of life manifest within 3-4 weeks, but maximum benefits take longer.

    · Effects on depressive mood appear after 3-6 weeks with a maximum after 18-30 weeks.

    · First effects on erythropoiesis (increased red blood cells) after 3 months, peaking at 9-12 months.

    · Prostate specific antigen and volume rise, marginally, plateauing at 12 months; further increase related to aging rather than therapy.

    · Effects on lipids appear after 4 weeks, maximal after 6-12 months.

    . Insulin sensitivity
    may improve within few days, but effects on glycemic control become evident only after 3-12 months.

    · Changes in fat mass, lean body mass and muscle strength occur within 12-16 weeks, stabilize at 6-12 months, but marginally continue to improve over years.

    . Effects on inflammation occur within 3 to 12 weeks.

    · Effects on bone detectable after 6 months but continue at least for 3 years.


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    For information on how to prevent or reverse side effects of testosterone, click here:

    Testosterone Side Effect Management Table

    The following graph shows how many weeks it may take for maximum results
    Attached Images Attached Images  
    Last edited by Nelson Vergel; 10-29-2015 at 01:08 PM.

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  3. #2
    Super Moderator Nelson Vergel's Avatar
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    Sep 2013
    Houston, Texas, United States
    More data on body composition changes caused by testosterone:


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