Questions about my TRT regimen and way to help things along

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CoastWatcher

Moderator
I have the exact numbers now. Anastrozole is 1mg tablet once a week. It was prescribed at the beginning of my treatment when I was taking Clomid.

Not very good at math. So the answer the internet gave me concerning my injection of 1ML of test cypionate every week is 1000 mg it told me.

Im trying to find an endocrinologist that works better for me (dont like the one im currently with) so I can get the test done about thyorid and pre-diabetes.
I can assure you, you aren't injecting 1000mg of testosterone every week. So...look at the vial. It should tell you XXXmg/ml.

Your anastrozole dose is a larger one than is normally seen.
 
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Vithat

Member
I can assure you, you aren't injecting 1000mg of testosterone every week. So...look at the vial. It should tell you XXXmg/ml.

Your anastrozole dose is a larger one than is normally seen.


Ooooh why didnt you say so. It says 200mg/ml

As for HCG it says 12000 IU

What does it mean?
 
M

MarkM

Guest
I do not mean any disrespect here when I say this but TRT is a life long therapy. You should try to get much more educated and knowledgeable on the subject, especially on what the dosage units mean on your prescritions to ensure you are taking the proper dose.


As far as your question "Is there anything bad that can happen on a high Anastrozole dose?" - Only if you want to feel absolutely miserable and hate getting out of bed. You want to avoid taking too high a dose of anastrozole or any aromatase inhibitor.
 

CoastWatcher

Moderator
Is there anything bad that can happen on a high Anastrozole dose?

Anastrozole suppresses estradiol levels. As MarkM notes, too much is a ticket to hormone hell. It is primarily used as an adjunctive therapy for women undergoing treatment for breast cancer who, on a temporary basis, need to eliminate estradiol. It works well for men who aromatize testosterone at such a level as to impede their TRT protocol; they need to manage their e2 level. But estradiol is a necessary hormone for men, it's not a waste product. Eliminate it and you impact sexual function, cognition, a whole host of things. It's a good drug for men on TRT, IF THEY NEED IT.
 
Last edited:

Vithat

Member
I do not mean any disrespect here when I say this but TRT is a life long therapy. You should try to get much more educated and knowledgeable on the subject, especially on what the dosage units mean on your prescritions to ensure you are taking the proper dose.


As far as your question "Is there anything bad that can happen on a high Anastrozole dose?" - Only if you want to feel absolutely miserable and hate getting out of bed. You want to avoid taking too high a dose of anastrozole or any aromatase inhibitor.

Im trying. I am easily overwhelmed with the information to sift through. Im just coming off of rehab and therapy for depression and am trying to figure a lot of things out.

So far ive gathered that I need to get my Thyroid checked properly as well as insulin resistance. I need to follow a ketogenic or low carb diet coupled with trying to lose weight which should mitigate insulin resistance, or try and get back on Metformin. I need to talk to my test doctor about the anastrozole and how it might be affecting me. I also need to figure out how to divvy up my 1ML of Test and 0.75 ML of HCG to every other day since I apparently need to up my injection frequency.

Thats everything everyone here has said. Is that the gist of it?
 

Blackhawk

Member
This blood was drawn at the end of May as I said.


This is not relevant to my comment about having blood drawn at trough. The trough is when you blood T level is at its lowest right before your next dose. So if you are injecting say on Monday morning 1x/ week, you should be having blood drawn early Monday morning, before you take your injection.


As I am just learning on how to inject, I dont know how particularly smart that would be atm. I do not know how to divide up the dose and whatnot for one. And my inexperience injecting might lead to an increased chance of infection or waste.


Good you have this self knowledge, but you HAVE to learn this. As stated, 1 dose per week is usually problematic and this is pretty much assured for someone with your SHBG. Your dosage frequency depends entirely on you SHBG level. You HAVE to study this and understand it. One 200mg dose per week is not appropriate for you.


This is just a lot information right now. Im trying not to feel overwhelmed.


Yes, it is a lot of information and can take time to learn and understand. You NEED to do so! There are numerous red flags that your doctor does not know what he/she is doing in terms of your treatment. You have to take responsibility for yourself in this regard. No one else will do it for you.


Ill have to get back to you on the measurements specifics. I do know its Cypionate and at 200mg/ml concentration.


Not very good at math. So the answer the internet gave me concerning my injection of 1ML of test cypionate every week is 1000 mg it told me.




These two statements entirely contradict each other. If your T cypionate is 200mg per ML then 1 ml equals 200mg, NOT 1000mg.


If you are injecting 1ml per week of 200mg/mg solution you are getting a single dose of 200mg per week.


This is a high dose and this level very commonly causes problems: High estradiol and hematocrit being the main ones,. Reasonable initial dose is usually 100mg per week to 150mg per week divided into number of doses based on SHBG. The lower the SHBG the more frequent the dosing.


Im trying to find an endocrinologist that works better for me (dont like the one im currently with) so I can get the test done about thyorid and pre-diabetes.


This is good. You should leave that doctor. Again, there are many red flags in your treatment indicating your doctor has no clue how to manage your TRT. Unfortunately it is very rare for an endocrinologist to have this knowledge. The traditional standards of endocrinology are seriously outdated, and old treatment protocols often do more harm than good. You need a specialist who actually understands up to date TRT issues. Finding that person can be a huge challenge.
 
M

MarkM

Guest
I know it can be overwhelming and we only wish to help. I've tried to make sense of this entire thread and you have been given some good advice. You do need to talk to your doctor about the anastrozole dose. If it were me, I would not take it anymore until you feel like you have symptoms of your estradiol skyrocketing. If you feel like you must take some I would not take more than 1/4 of the 1 mg pill until you speak with your doctor. You need o make sure that you have the right estradiol test. The right one is called Estradiol Sensitive and it is the "LC/MS/MS" assay. Your doctor should know what that is.


For the testosterone injections I can only assume you are supposed to be taking 100 mg a week. No way it is 1,000 mg a week. I would take 50 mg twice a week and split the week in half. So take the injections every 3.5 days. For example, I take mine Monday morning and Thursday evening. If you are using a 1 cc or 1 ml syringe (cc and ml is the same thing) then fill the syringe up to 0.25 since your testosterone is 200 mg/ml. Since your script is 200 mg/ml this will give you 50 mg of testosterone. If you do not have a 0.25 on the barrel of the syringe then just fill the syringe right in the middle of the 0.20 and 0.30 to get 0.25.



Since you are so young I would take the HCG but not 500 iu each day. You should clarify with your doctor but until such time I would just take 500 iu twice a week (the same day as your testosterone injection). If you are using the same type syringe, 1cc or 1 ml, then feel the syringe up to the 0.50.


You were smart to join the forum for help and to become more knowledgeable about your TRT protocol. These are just recommendations on my part and I am not an expert. I'm sure others more knowledgeable will weigh in to help further.
 
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CoastWatcher

Moderator
MarkM has given you a good, calm overview of where you stand and how to orient yourself so as to begin moving ahead. It is a shame that so few doctors don't understand the ins and outs of male hormone management. It means that the patient has to become his own advocate. But that isn't entirely a bad thing. It is our body, our health, our life; when our body breaks down its up to us to educate ourselves and step up.

Read ad the material in your thread. Spend some time reading the other threads, particularly the "sticky" threads in each folder. You can get a solid understanding of this issue and claim your rights as a patient.
 

Vithat

Member
I know it can be overwhelming and we only wish to help. I've tried to make sense of this entire thread and you have been given some good advice. You do need to talk to your doctor about the anastrozole dose. If it were me, I would not take it anymore until you feel like you have symptoms of your estradiol skyrocketing. If you feel like you must take some I would not take more than 1/4 of the 1 mg pill until you speak with your doctor. You need o make sure that you have the right estradiol test. The right one is called Estradiol Sensitive and it is the "LC/MS/MS" assay. Your doctor should know what that is.


For the testosterone injections I can only assume you are supposed to be taking 100 mg a week. No way it is 1,000 mg a week. I would take 50 mg twice a week and split the week in half. So take the injections every 3.5 days. For example, I take mine Monday morning and Thursday evening. If you are using a 1 cc or 1 ml syringe (cc and ml is the same thing) then fill the syringe up to 0.25 since your testosterone is 200 mg/ml. Since your script is 200 mg/ml this will give you 50 mg of testosterone. If you do not have a 0.25 on the barrel of the syringe then just fill the syringe right in the middle of the 0.20 and 0.30 to get 0.25.



Since you are so young I would take the HCG but not 500 iu each day. You should clarify with your doctor but until such time I would just take 500 iu twice a week (the same day as your testosterone injection). If you are using the same type syringe, 1cc or 1 ml, then feel the syringe up to the 0.50.


You were smart to join the forum for help and to become more knowledgeable about your TRT protocol. These are just recommendations on my part and I am not an expert. I'm sure others more knowledgeable will weigh in to help further.

Thank you for your reassuring response. Im goig to try my best to cut through all this information.

Concerning diet. Ive been trying to get that down for a while now. Right now Im hopping between diet to diet. Currently im doing a military diet (VERY small portions. Such as only 1 egg one slice of toast, one apple) Im not sure its worth it. Im combining it with intermittent fasting as well.

How difficult is it to stick to a Keto diet? Additionally, would a carnivore diet be even better if little to no carbs can provide such benefit?
 
M

MarkM

Guest
Thank you for your reassuring response. Im goig to try my best to cut through all this information.

Concerning diet. Ive been trying to get that down for a while now. Right now Im hopping between diet to diet. Currently im doing a military diet (VERY small portions. Such as only 1 egg one slice of toast, one apple) Im not sure its worth it. Im combining it with intermittent fasting as well.

How difficult is it to stick to a Keto diet? Additionally, would a carnivore diet be even better if little to no carbs can provide such benefit?

I have never been on a diet in my life. I have always tried to eat pretty healthy and watch what I eat. While diet is important I believe you are trying to do too many things at one time; rehab for depression, changing up TRT protocol, trying to educate yourself regarding TRT, changing diet protocols back and forth, and probably other things I’ve overlooked. Maybe you are trying to juggle to many things at one time. No wonder you feel overwhelmed.

You are a very young man with a long life ahead of yourself. Slow down and take one thing at a time. If you are capable of doing all these things simultaneously then that is fantastic. If not, decide which one is most important to you and attack it first.
 
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