1. #1

    Huge drop in testosterone

    I canít wrap my head around whatís going on with my hormone levels. Iíve been getting my blood checked 2-3 times a year, just out of curiosity. However, Iíve noticed recently my testosterone levels have drop almost 40%. Here is a quick run down of the blood work.

    - Winter 2014- 991 ng/dL
    - Spring 2015- 1024 ng/dl
    - Fall 2015- 1014 ng/dl
    - Spring 2016- 981 ng/dl
    - Fall 2016- 740 ng/dl
    - Summer 2017- 782 ng/dl
    - Winter 2017- 730 ng/dl
    - Spring 2018- 610 ng/dl

    Estradiol has increased slightly to 17.6 pg/ml (most recent test). Thyroid values are right where they should be, maybe T4 being on the higher end of the range. Most blood work was done before 9:30am, within 30-45 minutes of waking up. Except for spring 2016 which was at 11:43am.

    Iíll be getting new blood work done soon (total test, free test, sbgh, thyroid panel, estradiol, and dhea). I just canít understand why my levels have tanked so hard.

    Iím 26 years old. Since late 2016 Iíve definitely had less overall energy, drive/motivation, and libido. I just chalked that up to losing my job and starting a new stressful one (have quit this year). I stopped working out entirely around the same time.

    What do yíall think?

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  3. #2
    Moderator Vince's Avatar
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    1- Sleep well. At least 7 -8 hours and keeping proper sleeping hours.
    For reference click here

    2- Moderate alcohol consumption to no more than 2 drinks a day.
    Reference

    3- Exercise for an hour , 3-4 times a week. Do not over train since this can decrease testosterone.
    Reference

    4- Lower stress. Learn breathing exercises and set your phone up for alerts every 2 hours to remind you to take a deep breath.
    Reference

    5- Some men may be deficient in zinc. Zinc is needed for proper testosterone production. 30-50 mg per day plus 3 mg of copper should be enough.
    Reference

    6- Do not wear tight underwear. Let your testicles hang and cool off since high temperatures can affect sperm quality. Sleep in boxers or naked if you can to allow nocturnal blood flow and erections to your penis. It is nature's way to feed and regenerate your penis' tissues.
    Reference

    7- Lose weight if overweight. Probably the most effective way to increase testosterone
    Reference

    8- Avoid pesticide exposure and do not heat up your food in plastic containers. Toxins can increase the conversion of testosterone to estradiol, a female based hormone.
    Reference

    9- Have sex or masturbate. People who do tend to have higher testosterone. Even the use of Viagra has been associated with increased testosterone.
    Reference

    10- Be aware that certain medications can decrease testosterone. These drugs include Ketoconazole, prednisone and corticoid steroids, anabolic steroids, Tagamet, Acutane, Proscar, Propecia, chemotherapy, metformin, statins, ibuprofen, prostate cancer treatments, and others. Cocaine, excessive pot use, and other street drugs can also decrease testosterone.
    Reference
    Reference
    Reference
    https://www.excelmale.com/showthread...rone-Naturally
    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

  4. #3
    The mechanism behind the curtains is thyroid output can fluctuate so as SHBG changes your total testosterone will also fluctuate. Then you have the fact that testosterone fluctuates independently of the thyroid output of SHBG. So my point is if thyroid is in distress this could help explain the fluctuations in total testosterone.

  5. #4
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    Quote Originally Posted by Systemlord View Post
    The mechanism behind the curtains is thyroid output can fluctuate so as SHBG changes your total testosterone will also fluctuate. Then you have the fact that testosterone fluctuates independently of the thyroid output of SHBG. So my point is if thyroid is in distress this could help explain the fluctuations in total testosterone.
    Im not sure how to interpret that. My thyroid levels havenít hanged much and are right in the middle of reference ranges. Do you mind explaining a bit more?

  6. #5
    Quote Originally Posted by Uniquerabbit View Post
    Im not sure how to interpret that. My thyroid levels haven’t hanged much and are right in the middle of reference ranges. Do you mind explaining a bit more?
    Thyroid hormones levels are not static, they can and do fluctuate. When you workout SHBG can increase and decrease after 24 hours, important not to workout within 24 hours of a blood draw. You talked about the stress of losing a job, that will raise Reverse T3 which inhibits Free T3 which can lower SHBG, which can lower Total T and raise Free T. Stress, being sick will increases Reverse T3. Thyroid problems are mostly intermittent acting up only briefly, you draw labs and miss it completely.

    Run a hormone panel every week and you'll see levels fluctuate, labs are a snapshot in time of a moving target.

  7. #6
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    Quote Originally Posted by Systemlord View Post
    Thyroid hormones levels are not static, they can and do fluctuate. When you workout SHBG can increase and decrease after 24 hours, important not to workout within 24 hours of a blood draw. You talked about the stress of losing a job, that will raise Reverse T3 which inhibits Free T3 which can lower SHBG, which can lower Total T and raise Free T. Stress, being sick will increases Reverse T3. Thyroid problems are mostly intermittent acting up only briefly, you draw labs and miss it completely.

    Run a hormone panel every week and you'll see levels fluctuate, labs are a snapshot in time of a moving target.
    Alright, Iíve got you. Thereís a lot going on. Iíll be getting new labs drawn soon (low stress, not sick, not working out hard, solid eating habits, good sleep, no drinking) and Iíll see what it looks like.

    I suppose I was just surprised my levels dropped as hard as they did. If it was one or two tests that fluctuated, I would have wrote it off as ďnormalĒ fluctuations. However, at least in my eyes, it looked like my hormones fell off a cliff.

    Side question: does each person have their own ďnormalĒ? Like if my ďnormalĒ is naturally higher than what Iím now at, would I feel low testosterone symptoms, even though for many people my levels would be ďnormalĒ?

  8. #7
    Quote Originally Posted by Uniquerabbit View Post
    Alright, I’ve got you. There’s a lot going on. I’ll be getting new labs drawn soon (low stress, not sick, not working out hard, solid eating habits, good sleep, no drinking) and I’ll see what it looks like.

    I suppose I was just surprised my levels dropped as hard as they did. If it was one or two tests that fluctuated, I would have wrote it off as “normal” fluctuations. However, at least in my eyes, it looked like my hormones fell off a cliff.

    Side question: does each person have their own “normal”? Like if my “normal” is naturally higher than what I’m now at, would I feel low testosterone symptoms, even though for many people my levels would be “normal”?
    Your normal is different from my own, the moment I get into the 600 ranges I get terrible acne on a level not seen even in my teenage years. My normal is a bit lower than most guys, I suspect I'm very sensitive to androgens as my muscle harden fast when I up my dosage or switch from two injections a week to EOD. The different between twice weekly and EOD is profound!

    Your normal could be higher than 600, some men are past 1000 naturally so midrange for them is normal for me.

  9. #8
    Quote Originally Posted by Uniquerabbit View Post
    Im not sure how to interpret that. My thyroid levels haven’t hanged much and are right in the middle of reference ranges. Do you mind explaining a bit more?
    To understand thyroid levels better (NOT just TSH and FT4):
    Information on on testing....
    Read here:
    http://www.tiredthyroid.com/what-labs.html
    And here:
    http://www.tiredthyroid.com/optimal-labs.html
    and here:
    https://stopthethyroidmadness.com/recommended-labwork/
    and here:
    https://www.restartmed.com/thyroid-tests/
    and here:
    https://www.restartmed.com/hormone-testing/
    And here:
    https://www.restartmed.com/normal-thyroid-levels/
    **************************************

  10. #9
    "Estradiol has increased slightly to 17.6 pg/ml (most recent test). "
    Was that the SENSITIVE E2 TEST?
    If not, you need to run that test.
    Look around here for information for correct E2 test.
    also read here:
    http://www.peaktestosterone.com/Hdr_Estrogen.aspx

  11. #10
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    Quote Originally Posted by Orrin Israel View Post
    To understand thyroid levels better (NOT just TSH and FT4):
    Information on on testing....
    Read here:

    **************************************
    A lot of good info here. Thanks for sending all this. Iíll definitely need to see what the new tests show. This test will include T3 uptake, T4 free, T4 (thyroxine) total, and TSH. Iíll see what I can do about adding in the other recommended labs.

  12. #11
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    Quote Originally Posted by Orrin Israel View Post
    "Estradiol has increased slightly to 17.6 pg/ml (most recent test). "
    Was that the SENSITIVE E2 TEST?
    If not, you need to run that test.
    Look around here for information for correct E2 test.
    also read here:
    http://www.peaktestosterone.com/Hdr_Estrogen.aspx
    Yes sir, it was for sensitive E2. LabCorp performed, LC/MS/MS, estradiol sensitive 17.6, reference range: 8.0-35.0 pg/mL.

  13. #12
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    Quote Originally Posted by Systemlord View Post
    Your normal is different from my own, the moment I get into the 600 ranges I get terrible acne on a level not seen even in my teenage years. My normal is a bit lower than most guys, I suspect I'm very sensitive to androgens as my muscle harden fast when I up my dosage or switch from two injections a week to EOD. The different between twice weekly and EOD is profound!

    Your normal could be higher than 600, some men are past 1000 naturally so midrange for them is normal for me.
    Hmm... interesting. So using the numbers you provided, at what point would be the effects lowered testosterone be felt? As per your example, for you 600 is right where you need to be. For some men, they may need to be at 1000. If they were to drop to 600, would they feel low T symptoms/effects? Thatís a 60% reduction, so thatíd be the equivalent as youíre testosterone dropping to 360. Iím sure for you 360 would be rough and certainly would be considered low T. Is this he same for a guy who went from 1000 to 600?

    (
    obviously there are some parallels to my situation in the hypothetical, but Iím asking out of curiosity, not for a medical decision)

  14. #13
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    Quote Originally Posted by Uniquerabbit View Post
    Hmm... interesting. So using the numbers you provided, at what point would be the effects lowered testosterone be felt? As per your example, for you 600 is right where you need to be. For some men, they may need to be at 1000. If they were to drop to 600, would they feel low T symptoms/effects? Thatís a 60% reduction, so thatíd be the equivalent as youíre testosterone dropping to 360. Iím sure for you 360 would be rough and certainly would be considered low T. Is this he same for a guy who went from 1000 to 600?

    (
    obviously there are some parallels to my situation in the hypothetical, but Iím asking out of curiosity, not for a medical decision)

    You should not compare yourself to someone else let alone just shooting for numbers.

    Free T is the active fraction and it comes down to where your levels need to be regarding free T whether that requires you to have a mid-normal TT or high normal TT in order to get your free t where it needs to be (in order to feel relief/improvements of your low t symptoms ) and your shbg levels will play a big part in that.


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