5 weeks on TRT, still low on T and E2

iwasthatkid said:

Hi guys,

My T level prior to the TRT was at ~280. So I have been on 100mg/injection, 1 injection/week for 5 weeks. I injected on last Monday and got the blood work on last Friday. Some of the results and reference are as follows:


Testosterone is at 295, 264 - 916
SHBG is at 20.7, 16.5 - 55.9
Estrogen is at 57, 12-72
E2 (Roche ECLIA methodology) is at 5, 7.6-42.6 (low)

The full report is in the attachment.

I do not know why they did the Roche ECLIA instead of sensitive E2 after i specifically told them I wanted sensitive one though..... My understanding is that the sensitive results should be even lower than the Roche ECLIA method....

I'm still felling fatigue and tired all the time.

What protocol should I ask to switch to now?

Should I ask my urologist to increase my dose to 200mg/week or should I consider adding HCG to my protocol.? What's the dose and frequency for HCG if I add it? What are the other supplement or medication I should include?


Thanks a lot for any advice in advance!

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CoastWatcher said:

Welcome to Excelmale.

Your SHBG value suggests that a split-dose protocol would work. Multiple, smaller injections of testosterone over the course of the week are likely to have a far greater impact on your levels. Why was "estrogen" measured? It provides no actionable information. Future testing should be done at trough - just before a scheduled injection.

So...you paid for a test that is of no value (estrogen), the wrong estradiol test was ordered, and a protocol was designed that your SHBG argues won't work. Split your dose, 50mg every 3.5 days, wait six weeks, test appropriately...find a new doctor.

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Vince said:

I agree split your dose of testosterone and inject twice a week, add HCG. Do labs on injection day before you inject, wait at least 6 weeks before doing labs after changing protocol.

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iwasthatkid said:

In my case, what aspect will HCG benefit? Is it to boost my E2?

If i increase the injection to 150mg/week, do I still need the HCG to boost my E2?

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