Magnesium benefits in heart attack prevention

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Comparison of Mechanism and Functional Effects of Magnesium and Statin Pharmaceuticals. Andrea Rosanoff, PhD and Mildred S. Seelig, MD
http://mgwater.com/statin.shtml

A study published in The Lancet concluded that magnesium reduced the odds of death from myocardial infarction by 55 percent in a double-blind, randomized, placebo-controlled study of 2,316 patients with suspected myocardial infarction.
In a 1995 study, researchers found that the in-hospital death rate of those receiving intravenous magnesium was 25 percent of those who received standard treatment alone. In 2003, a follow-up study of these patients revealed a lasting effect of magnesium treatment. Nearly twice as many patients in the standard treatment group had died compared to those who received magnesium and there were considerably more cases of heart failure and impaired heart function in the placebo group. In addition to increasing survival after heart attack, IV magnesium smooths out arrhythmias and improves results of patients undergoing angioplasty with stent placement.The enzyme that deactivates HMG-CoA Reductase requires magnesium, making magnesium a Reductase controller rather than inhibitor. Magnesium is also necessary for the activity of lecithin cholesterol acyl transferase (LCAT), which lowers LDL-C and triglyceride levels and raises HDL-C levels. Statin drugs lower LDL-C levels more sharply than do magnesium supplements, but magnesium more reliably acts to improve all aspects of dyslipidemia including raising HDL-C and lowering triglycerides.Magnesium at optimal cellular concentration is well accepted as a natural calcium channel blocker.
 
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