New Mata-analysis of TRT Benefits

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Jinzang

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The full text of the meta-analysis is online

To the best of our knowledge, this is the first study to compare the benefits and harms of individual testosterone products among hypogonadal men. Our study builds on previous meta-analyses by comparing the relative effects of individual testosterone treatments, most of which have never been compared in head-to-head trials. When considered as a class (any TRT compared with placebo), TRT improved quality of life, depression, erectile function and libido; however, when the individual products were compared head to head, there were few differences between the treatments. We found no increased risk of major harms; however, this must be viewed in light of the high risk of bias of the included studies, the rare nature of serious harms, and the short treatment duration and follow-up of most studies.
 
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