TRT May Lower Prostate Cancer Risk and Severity

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Hypogonadal men who receive testosterone replacement therapy (TRT) may have a lower incidence of prostate cancer (PCa) than those not receiving TRT, according to study findings presented at the Sexual Medicine Society of North America 18[SUP]th[/SUP] Annual Fall Scientific Meeting in San Antonio, Texas. In addition, PCa diagnosed in TRT recipients is less severe than PCa diagnosed in men unexposed to TRT.

  • Urologists in Bremerhaven, Germany, and colleagues studied 400 hypogonadal men (testosterone level of 350 ng/dL or less) who received testosterone undecanoate 1000 mg every 3 months for up to 10 years and 376 hypogonadal men who opted against TRT (control group).
  • During a median follow-up of 8 years, 9 men in the TRT group (2.3%) were diagnosed with PCa compared with 26 (6.9%) in the control group. The incidence was 31 per 10,000 years in the TRT group compared with 95 per 10,000 years in the control group.

"Testosterone Therapy May Lower Prostate Cancer Incidence," Renal and Urology News, 14 November 2017, http://www.renalandurologynews.com/...tosterone-replacement-therapy/article/707168/
 
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