How is intratesticular estrogen measured, and how is it treated?

Austinite · Nov 28, 2013

I'm reading too much conflicting info and hoping someone can clear this up for me.

How is intra e2 measured? And if the common aromatase inhibitors are ineffective, what's the solution?

Gene Devine · Nov 30, 2013

From what I've learned over the years, intratesticular E2 can't really be measured as it's not in serum and an AI is largely ineffective in controlling it.

It can be a problem for some men especially when higher doses of HCG are used in protocol.

robs2nd75 · Nov 30, 2013

Would it present medically the same way elevated serum e2 does?

Gene Devine · Nov 30, 2013

robs2nd75 said:
Would it present medically the same way elevated serum e2 does?

Yes, my previous post was ambiguous. It is measured in serum; but for whatever the pharmacological reasons an AI does a poor job at slowing intratesticular aromatase synthesis.

Austinite · Nov 30, 2013

That's what is so mind boggling. I've read several studies about elevated intra E2, but none mention the method. There has to be a method if they can report results.

Nelson Vergel · Dec 1, 2013

We need the right amount of intratesticular testosterone and estradiol to produce healthy sperm and keep Leydig cells working properly. I have no idea why anyone would want to treat estradiol inside the testicles.

How is intratesticular estrogen measured, and how is it treated?

Austinite

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Gene Devine

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robs2nd75

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Gene Devine

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Austinite

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Nelson Vergel

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