Sex Hormones and Sleep in Men and Women

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Nelson Vergel

Founder, ExcelMale.com
J Clin Endocrinol Metab. 2016 Nov;101(11):3968-3977. Epub 2016 Jul 12.

Sex Hormones and Sleep in Men and Women From the General Population: A Cross-Sectional
Observational Study.

Kische H1, Ewert R1, Fietze I1, Gross S1, Wallaschofski H1, Völzke H1, Dörr M1, Nauck M1, Obst A1, Stubbe B1, Penzel T1, Haring R1.


Abstract

CONTEXT AND OBJECTIVES:

Associations between sex hormones and sleep habits originate mainly from small and selected patient-based samples. We examined data from a population-based sample with various sleep characteristics and the major part of sex hormones measured by mass spectrometry.
DESIGN, SETTING, AND PARTICIPANTS:

We used data from 204 men and 213 women of the cross-sectional Study of Health in Pomerania-TREND.

MAIN OUTCOME AND MEASURES:

Associations of total T (TT) and free T, androstenedione (ASD), estrone, estradiol (E2), dehydroepiandrosterone-sulphate, SHBG, and E2 to TT ratio with sleep measures (including total sleep time, sleep efficiency, wake after sleep onset, apnea-hypopnea index [AHI], Insomnia Severity Index, Epworth Sleepiness Scale, and Pittsburgh Sleep Quality Index) were assessed by sex-specific multivariable regression models.

RESULTS:

In men, age-adjusted associations of TT (odds ratio 0.62; 95% confidence interval (CI) 0.46-0.83), free T, and SHBG with AHI were rendered nonsignificant after multivariable adjustment. In multivariable analyses, ASD was associated with Epworth Sleepiness Scale (β-coefficient per SD increase in ASD: -0.71; 95% CI: -1.18 to -0.25). In women, multivariable analyses showed positive associations of dehydroepiandrosterone-sulphate with wake after sleep onset (β-coefficient: .16; 95% CI 0.03-0.28) and of E2 and E2 to TT ratio with Epworth Sleepiness Scale. Additionally, free T and SHBG were associated with AHI in multivariable models among premenopausal women.

CONCLUSIONS:
The present cross-sectional, population-based study observed sex-specific associations of androgens, E2, and SHBG with sleep apnea and daytime sleepiness. However, multivariable-adjusted analyses confirmed the impact of body composition and health-related lifestyle on the association between sex hormones and sleep.
 
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Davie72

New Member
having a little trouble understanding it. so they concluding more sleep means more weight loss? or better testosterone? or both?
 
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