All HCG is NOT the same. Your balls care.

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Gman86

Member
So just got my 60 day labs back recently, and it gave me a good insight on how the Pregnyl HCG is working. Protocol is 100mg Test/ week and 1,000IU HCG/ week. No AI. Both dosed EOD. 28mg of test EOD, and 270iu of HCG EOD. Labs were done the morning I was supposed to inject. Test brand is EmpowerRx and HCG brand is Pregnyl.

Total Test - 1855 (250-1100)
Free Test - 296.8 (35.0-155.0)
Estradiol - 70 (<29)
SHBG - 44 (10-50)

Obviously all that testosterone can't be from the testosterone alone at 100mg/ week. So a total testosterone level of 1855 is telling me that the Pregnyl HCG contributed quite a bit in regards to testosterone production. For the record, I have responded quite well to HCG in the past, but only to the Pregnyl brand. I've tried a few compounding pharmacy brands of HCG and they were not able to budge my numbers in the testosterone department, let alone work this well at raising T levels. Also, I know people might think that I dosed my testosterone improperly or something, but I'm a nurse, and have been for a while. I give multiple injections to patients everyday, and have easily given over a thousand injections in my lifetime. I know insulin needles like the back of my hand, and know how to dose them. These are my labs literally on 100mg/ week of test, and 1,000iu of HCG/ week, nothing else, I swear. I'm with Defy, and have been so extremely grateful to find such amazing, compassionate and understanding people/ doctors. I would never jeopardize losing them by going off my prescribed protocol or using any other compounds than prescribed. I honestly couldn't believe how high my testosterone level was when I saw my labs. I've never seen someone else on my protocol have near these results.

I just wanted to post this to show that on my protocol, these numbers are possible, but in my opinion based on my experience with HCG, these numbers might only be possible when using Pregnyl HCG or something similar to it, like Novel or Ovidrel. Basically anything other than compounding pharmacy HCG. These numbers could definitely be possible on compounding pharmacy HCG, don't get me wrong. I'm just saying I've never really seen it, and it's just my current theory, but I'm starting to think the reason men's testosterone levels aren't being raised much by HCG is due to what HCG they are using.

Last thing I want to add. I was on EmpowerRx HCG at the beginning of my protocol, and switched to Pregnyl after about 30 days or so. I never had labs done while on EmpowerRx HCG, so I can't say whether their HCG worked well or not. Clearly their testosterone cypionate works quite well, so I am very curious to what my labs would of looked like while still on their brand of HCG. They seem to make very high quality products. I just don't want to bash their HCG like I do the other brands that I have used. I never had labs done while on their brand, so I can't say either way whether it was effective or not.
 

tripinginoregon

New Member
I started by TRT journey with a Florida based anti aging clinic (not Defy) and the clinic was affiliated with a pharmacy that filled the scripts. Well, I was using 250iu twice a week of the compounded pharmacy HCG and my balls got high and tight and pretty much disappeared. I talked to my Rep and he advised to up the dose to 500iu 3x a week. I did that BUT I used some of my wife's Corion brand HCG and my balls came right back. I didn't put 2&2 together and thought it was the dose so when I ran through the Corion, I reconstituted one of the ones from the Florida Pharmacy and kept at the 500iu 3x a week. Well low and behold, my balls shrunk again. I realized that the issue wasn't the dose but the crap from the anti-aging clinic is bogus or completely underdosed. It can pass a pregnancy test but it's not the same strength as the Corion. That is crappy. So, I found one more vial of Corion laying around and voila, balls are back.

I have some Alpha-Pharma HCG and some Fertigen sp? that I got from India. I will try that next. This is why I'm looking for a good place that doesn't require a script to order Corion from. Beware gentlemen of shady pharmacies.

I too, was getting HCG from a Florida compounding pharmacy. I swear, it didn't do anything. I was taking it 500 twice a week. So I took a few drops and put them on a pregnancy test strip. It was negative. Makes me think the HCG wasn't any good.
 

Gman86

Member
Both of mine were from Florida pharmacies as well! United pharmacy and APS. Both of their HCG didn't work for me based off of multiple blood tests. Not only did they not work for me, but they suppressed my LH and FSH a bit, which actually lowered my testosterone compared to on nothing at all lol. I too tried to test them on dollar store pregnancy tests. It kept coming back with no result at all, not negative but not positive either, just blank the whole time. So I gave up trying to test them and I was too cheap to go buy more expensive pregnancy tests
 
So just got my 60 day labs back recently, and it gave me a good insight on how the Pregnyl HCG is working. Protocol is 100mg Test/ week and 1,000IU HCG/ week. No AI. Both dosed EOD. 28mg of test EOD, and 270iu of HCG EOD. Labs were done the morning I was supposed to inject. Test brand is EmpowerRx and HCG brand is Pregnyl.

Total Test - 1855 (250-1100)
Free Test - 296.8 (35.0-155.0)
Estradiol - 70 (<29)
SHBG - 44 (10-50)

Obviously all that testosterone can't be from the testosterone alone at 100mg/ week. So a total testosterone level of 1855 is telling me that the Pregnyl HCG contributed quite a bit in regards to testosterone production. For the record, I have responded quite well to HCG in the past, but only to the Pregnyl brand. I've tried a few compounding pharmacy brands of HCG and they were not able to budge my numbers in the testosterone department, let alone work this well at raising T levels. Also, I know people might think that I dosed my testosterone improperly or something, but I'm a nurse, and have been for a while. I give multiple injections to patients everyday, and have easily given over a thousand injections in my lifetime. I know insulin needles like the back of my hand, and know how to dose them. These are my labs literally on 100mg/ week of test, and 1,000iu of HCG/ week, nothing else, I swear. I'm with Defy, and have been so extremely grateful to find such amazing, compassionate and understanding people/ doctors. I would never jeopardize losing them by going off my prescribed protocol or using any other compounds than prescribed. I honestly couldn't believe how high my testosterone level was when I saw my labs. I've never seen someone else on my protocol have near these results.

I just wanted to post this to show that on my protocol, these numbers are possible, but in my opinion based on my experience with HCG, these numbers might only be possible when using Pregnyl HCG or something similar to it, like Novel or Ovidrel. Basically anything other than compounding pharmacy HCG. These numbers could definitely be possible on compounding pharmacy HCG, don't get me wrong. I'm just saying I've never really seen it, and it's just my current theory, but I'm starting to think the reason men's testosterone levels aren't being raised much by HCG is due to what HCG they are using.

Last thing I want to add. I was on EmpowerRx HCG at the beginning of my protocol, and switched to Pregnyl after about 30 days or so. I never had labs done while on EmpowerRx HCG, so I can't say whether their HCG worked well or not. Clearly their testosterone cypionate works quite well, so I am very curious to what my labs would of looked like while still on their brand of HCG. They seem to make very high quality products. I just don't want to bash their HCG like I do the other brands that I have used. I never had labs done while on their brand, so I can't say either way whether it was effective or not.

That's much more about you being Primary Hypo than the HCG which you make a very good point.
 

Gman86

Member
Hey whatsup Vince, nice to get a reply from one of the legends of this forum ;). But I'm actually secondary. First ever blood test, before treatment 3 years ago, had my LH at 3.3 (1.5-9.3). Plus when I first started out I was on HCG mono therapy with Pregnyl, and on two different blood tests my total testosterone came back at 1185, and then 1193. Those tests were done about 2 1/2 months apart. I was on 2,000iu/ week during each test. I was also on 2,000iu/ week while I was on the compounding pharmacy brands, and total testosterone came back at 559 on the first test, and 348 the second test.
 

Gman86

Member
No way, the other Vince replying too? Feel like I'm talking with celebrities lol. But seriously, you guys are both huge contributors to this forum, and we all appreciate it. But anyways, I think I have noticed a little more since switching to Pregnyl. The main thing I definitely noticed was an increase in testicular size. Probably about 25-30% going from even EmpowerRx's HCG to Pregnyl.

I currently have low to no libido. Erections are no problem, but my sex drive is still not there. I think that has a lot to do with my E2 being 70. I'm working on lowering that now, so I'm hoping my sex drive returns when my E2 gets within range. Once my libido comes back, my theory is that my semen amount during ejaculation will increase. I could be wrong on that tho since some men just on testosterone with high libidos have reported low ejaculate amount. But I'm curious to see if the amount for me does increase while on Test + HCG when my libido returns. But to answer your question again, I do think I noticed a small increase when switching to Pregnyl, but nothing very significant.
 

ratbag

Member
I use Corion C 5000iu from ReliableRx, a No Rx online pharmacy. I've tried other brands online and I found they didn't work at all for me. I'm hypopituitary so I can feel when it works and when it doesn't. Discussions on other sites also confirm that Corion C is one of the best and some say the strongest HCG available. I concur on all aspects. I tried Ovidac and it didn't work at all...the only name I remember that didn't work. Just wanted to throw that out there.
 

user_joe

Member
I've always been able actually feel a difference a few hours afterwards with a dose of hcg of 300iu or more. Clinic used a brand name pharma hcg(can't recall name). The past 1.5 yrs or so it's always been empower. Consistent results. I find the only real benefit is maintaining testicle size and function. I split my 500 weekly dose by backloading into my daily cyp injection. Without fail I'd get acne the day following larger doses of hcg.

Not entirely sure i even need it honestly, but it's pretty cheap, and it would be odd to have really small balls. Lol. Even with low T that never really happened.
 

Zooka15

Member
My Doc told me compounding pharmacies use rHCG and pregnyl is uHCG....Basically compounded is synthetic , where pregnyl is derived from pregnant women.
 

Vince

Super Moderator
I do use Empower T and HCG, my libido is excellent but very low in ejaculate amount. My girlfriend likes the low semen and when I'm cuming it feels like it's a lot. But it would be nice to produce more.
 

tripinginoregon

New Member
I do use Empower T and HCG, my libido is excellent but very low in ejaculate amount. My girlfriend likes the low semen and when I'm cuming it feels like it's a lot. But it would be nice to produce more.

Is there an online pharmacy you recommend? I'd like to get Pregnyl. I had a prescription for it from my doctor, but every pharmacy I went to was out of stock and the manufacturer wouldn't give a date when they would ship it. I tried Walmart, Rite Aid, Walgreens, etc. Ended up getting it from a compounding place in Florida, but it didn't do anything.
 

CoastWatcher

Moderator
I do use Empower T and HCG, my libido is excellent but very low in ejaculate amount. My girlfriend likes the low semen and when I'm cuming it feels like it's a lot. But it would be nice to produce more.
I, too, have seen my ejaculate volume drop since starting TRT. My doctor has said its a typical side effect, one she's seen in the vast majority of her patients. I believe Dr. Saya has noted that it's a common issue men experience on TRT. You're right, though, about the subjective sense of releasing far more than is actually produced.
 

ratbag

Member

Vince

Super Moderator
Is there an online pharmacy you recommend? I'd like to get Pregnyl. I had a prescription for it from my doctor, but every pharmacy I went to was out of stock and the manufacturer wouldn't give a date when they would ship it. I tried Walmart, Rite Aid, Walgreens, etc. Ended up getting it from a compounding place in Florida, but it didn't do anything.
Sorry, up to now I've only received my HCG from APS and Empower.
 
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