Consultation with Defy in 7 Weeks: Will Weight Loss Skew My Test Results?

I have an initial consultation with Dr. Saya at Defy in 7 weeks. I am starting a diet to cut some weight at the moment, and am worried that, by the time I see him and then wait another 6-12 weeks for the next follow up, my testosterone results will be impacted by the reduction in bodyfat, making it hard to isolate the variable of the treatment.

Should I wait until I am lean to re-test bloods and have a first consult?

Coolrunnings22 said:

I have an initial consultation with Dr. Saya at Defy in 7 weeks. I am starting a diet to cut some weight at the moment, and am worried that, by the time I see him and then wait another 6-12 weeks for the next follow up, my testosterone results will be impacted by the reduction in bodyfat, making it hard to isolate the variable of the treatment.

Should I wait until I am lean to re-test bloods and have a first consult?

Click to expand...

I'm confused, you don't already have lab work done?

Generally, reduction of body fat does not result in a meaningful increase in testosterone levels. Most of the studies I have seen show a 100ng/dl increase if anything.

You can always order labs before the consult, but AFAIK they require you to have labs at the time of scheduling the consult.

Yes, I have already had lab work done and have scheduled the consult. Thanks for your thoughts - I had assumed fat loss would have more of an effect

Coolrunnings22 said:

Yes, I have already had lab work done and have scheduled the consult. Thanks for your thoughts - I had assumed fat loss would have more of an effect

Click to expand...

Don't worry about the weight loss changing your labs, your protocol will be adjusted as you get dialed in. Get started and lose that extra weight.

Coolrunnings22 said:

Yes, I have already had lab work done and have scheduled the consult. Thanks for your thoughts - I had assumed fat loss would have more of an effect

Click to expand...

Weight loss produced significant increases in mean plasma total testosterone [240 ±116 (±sd, 8.5 ± 4.0) to 377 ± 113 ng/dL (13.0 ± 4.0 nmol/L); P < 0.01], free testosterone [9.5 ± 5.0 (329 ± 173) to 13.4 ± 4.3 ng/dL (464 ± 149 pmol/L); P < 0.025], and FSH (6.5 ± 4.7 to 10.9 ± 8.5 IU/L; P < 0.025). Plasma LH was lower than levels in normal men before and after weight loss and did not change significantly (10.3 ± 4.8 and 10.8 ± 6.8 IU/L, respectively). There was no change in plasma total E2 [54 ± 26 (196 ± 94) to 50 ± 13 pg/mL (180 ± 50 pmol/L)], free E2 [1.48 ± 0.7 (5.37 ± 2.54) to 1.33 ± 0.42 pg/mL (4.83 ± 1.45 pmol/L)], or total estrone [75 ± 38 (280 ± 140) to 82 ± 24 (300 ± 90) pmol/L], and sex hormone-binding globulin rose from 9.2 ± 3.2 to 12.9 ± 5.4 nmol/L (P < 0.005)


http://imgur.com/5cDOGhh


http://imgur.com/wN7D5bi


http://imgur.com/R0N757x


http://imgur.com/jWunKDz


So you can go from 250 to 350, or 350 to 450. I don't think many here would agree that this is helping anything. Personally I think it would hurt us more, as now we're too high to even get treatment.




https://academic.oup.com/jcem/artic...-Loss-on-Hypothalamic?redirectedFrom=fulltext