Eight Weeks on TRT - Feeling No Better

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Defy Medical TRT clinic doctor
your e2 is pretty low.. for me if e2 is low enough I lose the mental benefits of testosterone, you might want to raise it atleast to 20 pg/ml
 

Sean Mosher

Member
May or may not feel better with a higher Total T (that's something to look at).
Prolactin to high and estradiol WAY too low.....

What's your current protocol look like?
 

Libra88

New Member
Protocol:

70mg Test cyp 2x aweek
HCG 400IU 2x a week
anastrozole .125 3x a week

I also take cabergoline .5mg 2x a week

I spoke with Dr. Saya in this forum and he told me to lower the AI to 2x a week, but also told me because my SHBG is in the lower range of normal that more of the free estradoil can be used in the body, so my estradoil technically isn't REALLY low. He also uptitrated my cabergoline dose to help lower the prolactin. I updated my protocol a week ago, but still have no energy, motivaton, ED, low libido, etc,...literally all symptoms of low T.
 

Libra88

New Member
my prolactin was at 20, so with my initial consult Dr. Saya had me up my dose of cabergoline and now its at 40, so he told me to updose it again.
 

Vince

Super Moderator
Sounds like you're​ having some issues getting dialed in, hitting that sweet stop. Stick with Dr Says protocols and hopefully it will get better.
 
The prolactin and E2 (though taking into consideration the free E2 as we discussed prior) are both likely contributors. Would be interesting and informative to add the free estradiol test to your next labs, unfortunately is a very expensive test (~$100), which is why I don't utilize it as much as I would like.
 

Libra88

New Member
The prolactin and E2 (though taking into consideration the free E2 as we discussed prior) are both likely contributors. Would be interesting and informative to add the free estradiol test to your next labs, unfortunately is a very expensive test (~$100), which is why I don't utilize it as much as I would like.

Dr. Saya, whatever test I need done to make me feel better I am willing to take. I am just tired of living life the way that I am. I've been dealing with low T for over 10 years and now I am 28. Your next avaliable appointment is May 30th, I have an apoinment on May 10th with one of your doctors. I was wondering if I can talk to you for my appointnent on May 10th because I have a unique case if possible. I would really appreciate it.
 

Will Brink

Member
Protocol:

70mg Test cyp 2x aweek
HCG 400IU 2x a week
anastrozole .125 3x a week

I also take cabergoline .5mg 2x a week

I spoke with Dr. Saya in this forum and he told me to lower the AI to 2x a week, but also told me because my SHBG is in the lower range of normal that more of the free estradoil can be used in the body, so my estradoil technically isn't REALLY low. He also uptitrated my cabergoline dose to help lower the prolactin. I updated my protocol a week ago, but still have no energy, motivaton, ED, low libido, etc,...literally all symptoms of low T.

That's what I was going to suggest, so looks like a change that may help.
 
Dr. Saya, whatever test I need done to make me feel better I am willing to take. I am just tired of living life the way that I am. I've been dealing with low T for over 10 years and now I am 28. Your next avaliable appointment is May 30th, I have an apoinment on May 10th with one of your doctors. I was wondering if I can talk to you for my appointnent on May 10th because I have a unique case if possible. I would really appreciate it.

Unfortunately that would require moving another patient out of their appt slot.

The changes that we recently discussed over the forum (with cabergoline for prolactin and downward adjustment in anastrozole) need time to impact (thus waiting actually would be ideal for this reason). The providers under me are trained well and often review complex case questions with me.
 

ERO

Member
I am curious about the free estradiol test. Specifically, what part of the protocol would be changed based upon the results. Please keep us in the loop going forward!
 
I am curious about the free estradiol test. Specifically, what part of the protocol would be changed based upon the results. Please keep us in the loop going forward!

What is believed to be low (total) estradiol may occasionally turn out to not be low at all or even high (free estradiol).
 

Libra88

New Member
Ok that is fine, I also hope that I can raise my Testosterone/HCG dose so that I can achieve the highest optimal Testosterone levels. I plan on becoming a personal trainer or something to do with fitness and know how important Testoterone is. Will the doctor allow me to have a higher Test level as long as I keep track of my hemocrit levels, PSA, etc.? Thanks again for the replies!
 

Libra88

New Member
I also forgot to mention, now that I am doing the anastrozole twice a week, is there a certain time I'm supposed to do it? Also I am wondering why my LH/FSH was not tested just to see how the HCG is working in my body?
 
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