Regular/sensitive comparison

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I just had both the regular and the sensitive same exact draw. Sensitive was 31.4 and standard was 38. My energy and libido are not so hot. Do you you think getting my estradiol lower or higher would be a good direction to go? Currently injecting every 3.5 days and taking .25 mg anastrozole 24 hours after each injection. Blood draw was at trough right before my next shot. My testosterone is over 1000 and free t is in 20s. My tsh and free t3 are both sitting nice too. Vitamin d is 60. Only thing I havnt tested is b12. I feel like my estradiol is what needs tweaking. Honestly just not sure based on those numbers if i should try to lower it more or let it rise. So many different opinions on estradiol....
 
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I just had both the regular and the sensitive same exact draw. Sensitive was 31.4 and standard was 38. My energy and libido are not so hot. Do you you think getting my estradiol lower or higher would be a good direction to go? Currently injecting every 3.5 days and taking .25 mg anastrozole 24 hours after each injection. Blood draw was at trough right before my next shot. My testosterone is over 1000 and free t is in 20s. My tsh and free t3 are both sitting nice too. Vitamin d is 60. Only thing I havnt tested is b12. I feel like my estradiol is what needs tweaking. Honestly just not sure based on those numbers if i should try to lower it more or let it rise. So many different opinions on estradiol....

Post the full results for full comments.
 

Vince

Super Moderator
I just had both the regular and the sensitive same exact draw. Sensitive was 31.4 and standard was 38. My energy and libido are not so hot. Do you you think getting my estradiol lower or higher would be a good direction to go? Currently injecting every 3.5 days and taking .25 mg anastrozole 24 hours after each injection. Blood draw was at trough right before my next shot. My testosterone is over 1000 and free t is in 20s. My tsh and free t3 are both sitting nice too. Vitamin d is 60. Only thing I havnt tested is b12. I feel like my estradiol is what needs tweaking. Honestly just not sure based on those numbers if i should try to lower it more or let it rise. So many different opinions on estradiol....

I definitely wouldn't lower your E2, have your tried not using an AI.
 
Estradiol 38.3 range 7.6-42.6
Sensitive estradiol 31.4 range 8-35
Testosterone 1211 range 348-1197
Free testosterone 25.8 range9.3- 26.5
Vince I've tried .25 mg ai once a week instead of twice felt my erections weren't a solid might not have been related though. Never tried no ai.
 
your E tests have lab ranges that I'm unfamiliar with...was that labcorp, quest, or some other lab? Does your lab report indicate the sensitive was LC/MS/MS?????

I've done this once before and had my sensitive come back, higher, than the standard. Same day same draw, same lab...

Besides not testing in your trough if you continue to just dose Anastrozole at-will...curious way your approaching things given your time on this forum. Not posting your labs in post #1, tossing AI around, not testing in your trough...sigh
 
I said in my first post I tested at trough. Those are the basic ranges at labcorp. 8-35 range has been labcorps sensitive estradiol range for a least two years now.
 

JakeH

Member
I said in my first post I tested at trough. Those are the basic ranges at labcorp. 8-35 range has been labcorps sensitive estradiol range for a least two years now.

Yeah I thought your post was clear and to the point, so I am not sure what his deal is this morning. Anyway, I have read other experiences that for some guys E2 in range via the use of an AI makes them feel bad, while keeping E2 in range via a lowered dose of Test/more frequent shots WITHOUT AI makes them feel much better. Just a thought. I am trying to dial this in myself now, as taking an AI does not make me feel great.
 

Zooka15

Member
If you tested at trough your T levels are a little over range. You could lower T dose and get rid of the AI. Or just try stopping the AI for a bit. You have to understand also that high T can cause libido issues, ED, and fatigue for some. As it can mess with neurotransmitters and other hormones. At looking at your replies you are fixed on E2. Just advice, you might do better at total T of 800....just something to try
 

CoastWatcher

Moderator
Zooka15, JakeH, and Vince make a solid point. Consider modifying your protocol to the point of possibly eliminating the need for an AI. Give it some thought.
 

Dolcevictory

New Member
Jake


I wanted to write you and see how you were doing because I recently read your thread about weaning off Cialis and it resonated with me. I am 32 and also experience impotence however, just like yourself believe it is performance anxiety. I have nearly lost my girlfriend and its been a profound moment in my life. I did not face the issue for years and am finally out of denial. I can get erections but just lose them quickly. I am also looking into testosterone. I just received my first generic Cialis literally yesterday and obviously my goal is to wean off it eventually.


How has your progress been? Have you experienced success? Any milestones?
 
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