1. #1

    New member 42 years old

    Hey all,

    New member and first time posting. I have been on TRT (test cyp 100 mg weekly) for about 2 years.

    About 6 months from my 40th birthday my marriage fell apart and I felt horrible mentally and physically. I am 6 feet tall and at the time weighed in at 345 lbs. this is the most i have ever weighed. I tried hitting the gym but had no energy and my strength was gone. I was struggling with 20 lb dumbbells when in my prime I was working out with 90 lb dumbbells. I knew something was not right. I went to my doctor and he ordered some tests and diagnosed me as hypogonadal. No brain tumors or history of testicular damage. I started on Androgel which after 3 months proved ineffective so moved to injection.

    Initial total serum test 259 ng/dl range 348 to 1197

    follow up tests
    total serum test 232 ng/dl 348 to 1197
    free test 38 pg/ml range 46 to 224

    Vit D was almost non-existent.

    It has been about 2 years and I have seen many benefits. My strength has returned and I am stronger now than I have ever been. I am down 20 lbs overall based on the scale but have filled out when it comes to musculature. I have always had broad shoulders but have gone from a 54 to a 58 and have had to throw out my suits and sports jackets. I have lost fat everywhere except my mid section. I really seem to hold on to that and am struggling there. My diet has not always been the greatest and I know I can do better there.

    Area where I have not seen improvement is erections. I can't remember the last time I had "morning wood" and erections are weak and do NOT last. Being the marriage fell apart 2 years ago sex is not plentiful so was put on the back burner to work on my mental and physical health. I would like to correct this part of my life

    I did not know about estrogen management when I started so have no baseline info so just had those levels measured last week.

    Estradiol was 50 pg/ml range < or equal to 39
    total serum estrogen 209.1 pg/ml range 60 to 190

    Total serum test 388 ng/dl 250 to 827
    free test 97.6 pg/ml range 46 to 224

    i also hold water Especially in my legs and feet and feel bloated 3 to 4 days a week.

    I am open to any advice from everyone's experience and looking forward to,learning all I can.

    thanks for listening

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  3. #2
    You're being given the wrong Estrogen tests, you need the test for males, (Ultra)Sensitive, Estradiol, LC/MS/MS...this is the only test you need and this is for males. The test you received is for females and (typically) overestimates Estrogen in males.

    Bloat and water retentin those few days with your injection and tapers off at the end of the week prior to your next shot?

  4. #3
    Super Moderator Gene Devine's Avatar
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    Hi and welcome to Excel Male...you've come to the right place.

    First and foremost, you need to learn everything you can about TRT for men and it's all here for you to do that and why we created the site and forum.

    As far as what you posted re your blood work; your serum testosterone levels are terrible and at the bottom end of the reference range.

    Also, estrogen needs to be tested using the "Sensitive" lab and not the standard lab designed for women so it's really useless.

    Need to know what your TRT protocol is; dosages, frequency, use of HCG...

    Something is not adding up; to be on TRT and have the levels that you posted says something is wrong with what you are doing.

    Is your Doctor well trained in TRT for men...and I have a strong suspicion that's not the case or else you'd have better serum levels.

    Your erection issues can be caused by a lot of things one of which is elevated and/or suppressed estrogen levels and holding water is another red flag on elevated estrogen.

    Can you post your most recent labs here please?
    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

  5. #4
    I'd bet he's low SHBG with those troughs

  6. #5
    Super Moderator Gene Devine's Avatar
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    Quote Originally Posted by Vince Carter View Post
    I'd bet he's low SHBG with those troughs
    Or every two week injections!!!
    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

  7. #6
    I inject weekly 100mgs test cyp. No hcg and no AI's. my serum levels usually are ~650. I did miss a dose in the last 3 weeks.

    SHBG was 40 when last measured. Range 27.9 to 146.0 nmol/L. This was just prior to starting on my current protocol.

    I have been working with an endocrinologist but he is not a men's health specialist.

  8. #7
    Super Moderator Gene Devine's Avatar
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    If you're injecting 100 mg weekly and your serum levels are test 388 ng/dl (250 to 827) free test 97.6 pg/ml range 46 to 224 then you need to increase your dosage.

    Still something seem suspect here....
    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

  9. #8
    Hey Gene,

    thanks for for your comments. I really appreciate your time. I am not sure by what you mean by suspect?

    I did miss a dose within the last few weeks per my last post and my trough levels are usually around 650. I am guessing I am going to need a few weeks to normalize from the missed dose. Agreed 388 is not a good number.

    i have ordered the sensitive estradiol test from discounted labs and will post results once I have them and will instruct my Dr to order that test.

    Question though - how did you know my original test was not the sensitive estradiol test?

    thanks again for listening.

  10. #9
    Because of the lab ranges...the proper test has a lab value shown as <29, the test you took is < or equal to 39, we learned to know what's what by the ranges.

    By suspect I think we mean something isn't being expressed right as we know how the math typically plays out something is different with your numbers. Are you having your blood drawn in the morning, right before your due for an injection? That is the ONLY time you should be testing. Also, please do what you can, don't miss a dose, if you miss a day get back on the next day, it's very important to stay steady and consistent through your therapy.

  11. #10
    Yes. I always have blood drawn in the morning and inject after I get home.

  12. #11
    You noted that you've been on TRT for two years; do these most recent results mirror what you've posted in the past?
    I am not a physician. Comments offered here are for discussion purposes only. Please consult your doctor before initiating, changing, or stopping any therapy.

  13. #12
    Super Moderator Vettester Chris's Avatar
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    Mathew, thanks for signing up with EM! Great comments above! The only thing I might add is if you can post a complete set of labs (scan image is fine), with CBC's, lipids, metabolic, thyroid, etc., the forum will have more to discuss, plus there could be other factors for talking points that might be relevant to your current situation?
    Please, no PM's posting lab results ... Let's Keep them on the Open Forum for Everyone to Comment. Feel free to PM me a link to your thread if you would like me to comment. Thanks!!


    I am not a Doctor, I only play one on T.V. Please consult your physician, or a trained-licensed physician before proceeding with any comments or suggestions posted on this or any forum.


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