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  1. J

    High estradiol even on anastrazole

    Since my wife started with Defy, she's questioning everything we used to accept. In retrospect, I should've questioned changing doses, levels and adding meds rather than blindly handing it off to my doctor. Thankfully the members on this site are pointing me in the right direction with some...
  2. J

    High estradiol even on anastrazole

    Agreed - the high T seems to be the most pressing issue and professional oversight from Defy would be best. Thank you for confirming!
  3. J

    High estradiol even on anastrazole

    Wow. Thank you for taking the time to explain all of this so thoroughly. I now understand how to correctly reference the dosage so currently I’m at 200mg injected once weekly. As suggested by someone else, I guess the HCG could be further exasperating the issue. I understand what you’re saying...
  4. J

    High estradiol even on anastrazole

    More and more I’m thinking my wife’s care with Defy outranks what I’m getting. (I just don’t want to admit to her she was right) The HCG was added because of my shrinking testicles and low sperm volume. It’s probably exasperating rather than correcting the issue
  5. J

    High estradiol even on anastrazole

    So I read your info and it's making some sense; forgive me for the following stupid questions but I'm really new getting hands on with my healthcare. I am at 200mg and what's interesting to me was that last fall I was at .5 T instead of 1mg weekly. My T level was 700 and my E was 40. I felt...
  6. J

    High estradiol even on anastrazole

    This is really interesting info; I'll read the links- thanks for posting them! I did not know that was an option for dosing - thank you!
  7. J

    High estradiol even on anastrazole

    I'm on a morphine pump for chronic back pain and my testosterone dropped to 190. For two years I've been on 1 mg of testosterone cypionate weekly (ships from Empower Pharmacy) and donate blood regularly to keep my hematocrit/hemoglobin levels in check. Last year my estradiol levels were...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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