What drives E2 and HCT - Peaks vs Troughs?

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S1W

Well-Known Member
I've seen it mentioned from time to time that that T level peaks have the strongest affect on E2 and that T level troughs have the strongest affect on HCT. For example, if you want to lower E2, reduce the spikes in your T levels, which is often accomplished by more frequent injections. If you want to lower HCT, you would need to reduce your overall T dose so that your trough sits lower.

Do any of you have any opinions or experiences with this?

Common sense would lead me to believe that the overall average level of T within a dosage cycle would be what drives both, but I've seen this mentioned enough that I thought it would be interesting to hear about other experiences.
 
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Vince

Super Moderator
It appears that may be true for some members, but not for everyone. Some still struggle with estrogen and HCT even with daily injections.
 
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