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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What are the side effects of high testosterone?
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<blockquote data-quote="tareload" data-source="post: 212104"><p>And to clarify, I'm speaking about potential risks of running your testosterone above your original hypothetical functional setpoint. At 18 years old was your peak TT level 400, 600, 800 ng/dl? Maybe you never had one and you've always been HH. For those that voluntarily go on TRT/TOT (because their PCP would never in a million years prescribe Testosterone), a word of caution.</p><p></p><p>Pre-TRT were you at 350 ng/dl peak? What's the risk now that you are running 1200 ng/dl (peak) and 500-600 ng/dl (trough). You are still "in range" from a population/95% distribution standpoint. But, so what? That still may be supraphysiologic for you. When you get into all the ion transporters in the body, all sorts of feedback loops, gene expression, receptors, etc, etc we have no idea what's going to happen 5-10 years down the road. All quite individual. It's the TRT/TOT equivalent of <a href="https://en.wikipedia.org/wiki/Goldman%27s_dilemma" target="_blank">Goldman's Dilemma</a>.</p></blockquote><p></p>
[QUOTE="tareload, post: 212104"] And to clarify, I'm speaking about potential risks of running your testosterone above your original hypothetical functional setpoint. At 18 years old was your peak TT level 400, 600, 800 ng/dl? Maybe you never had one and you've always been HH. For those that voluntarily go on TRT/TOT (because their PCP would never in a million years prescribe Testosterone), a word of caution. Pre-TRT were you at 350 ng/dl peak? What's the risk now that you are running 1200 ng/dl (peak) and 500-600 ng/dl (trough). You are still "in range" from a population/95% distribution standpoint. But, so what? That still may be supraphysiologic for you. When you get into all the ion transporters in the body, all sorts of feedback loops, gene expression, receptors, etc, etc we have no idea what's going to happen 5-10 years down the road. All quite individual. It's the TRT/TOT equivalent of [URL='https://en.wikipedia.org/wiki/Goldman%27s_dilemma']Goldman's Dilemma[/URL]. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What are the side effects of high testosterone?
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