Tread lightly with 200 mg/ml Testosterone Cream . . . My experience

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Gunga

Member
I have been on TRT since 2013. Long boring story but recently switched from daily Cypionate injections to transcrotal cream and just wanted to share my tale for others with regards to dosing:

started 20% cream six weeks ago 2 clicks am AND pm all applied to the scrotum labs were crazy!

Total Testosterone >1500 6 hours post application
Free T 47.1

Then I tried 3 clicks per day 2 am AND 1 pm labs are still crazy!

Total Testosterone >1500 6 hours am application
Free T 45.4

Total Testosterone 773
Free T 25.7

Second reading is trough reading before am application

Again, I continued the experiment and tried 2 clicks am but only 1 scrotal. The other was back of the knees

Total Testosterone 1086
Free T 26.4.

I kept reducing dose because sides were awful. Couldn’t sleep. Woke up feeling my heart pounding through my chest. ED surprisingly. Anxiety. Short fuse. Etc.

I’m testing tomorrow as I’m beginning treatment with Dr Saya at Defy next month My current physician is a solid guy but doesn’t understand the strength of this stuff. His standard starting protocol is way to aggressive in my opinion. I need a pro to guide me through this. In the interim I’m feeling A LOT better by reducing dose down to 2 clicks per day 50% scrotum. 50% back of knees, 1 am and 1 pm. I know it sounds random but it works! I bet my trough reading will be 600-700 ish. Just wanted to share my story to potentially help some else out!!!

Tread lightly!!!
 
Defy Medical TRT clinic doctor

Gunga

Member
at15 I felt ok on daily Cyp injections. 12 mgs per day got me to 881 Total. Maybe it was still to high for me. My SHBG is 24. It’s taken me a while to get it through my thick skull that I do better on smaller doses.

That’s interesting Vince. I suspect I might try a Combination protocol next. I do notice a nice DHT induced libido boost when my dose is at appropriate levels that I did not get from injections only.
Thanks guys!
 

Renman23

Active Member
I use 200 mg cream, I apply on my forearms and not transcrotal. I have a bit too much belly fat and am concerned about conversion. I also find that once a week use of an AI (Anastrazole .125) helps to keep the estrogen symptoms away.
 

Gunga

Member
Renman 23 I'm with you. I don’t like using AI’s but I had to to get things under control as my ED was bad even with Cialis! I suspect I’m going to need a low dose AI until I lose about 15lbs and reduce body fat. Hopefully that would reduce my aromatization rate. I don’t understand the unlimited estrogen is ok crowd. Would never work for me.
 

Renman23

Active Member
I get the hesitation... I understand that Estrogen crash caused by getting the AI dosage wrong is bad.... But 2-3 weeks in to my first TRT .... I found myself sitting in my car, in the driveway @ 2am with the windows open because it was too hot in my apartment and i couldnt breathe...... Small dose of Anastrazole has helped me...
 

wondering

Active Member
200mg cream is pretty stout I only use 50mg/mL and then its just 1 click or 12.5mg twice per day to the scrotum which supplements my 10mg/D Cyp.

Is my recollection off or do you only supplement the cream occasionally. If so, do you notice subjective improvement in libido and ED doing it this way. If so, how often do you apply.

I have T cream, but if I could get benefit using occasionally I would prefer that vs constant high DHT and accelerating MPB. I am on 3x week Test Cyp as well.
 

Gunga

Member
Vince what are your levels with that protocol? (Total T/Free T) Sounds like something that could work for me as I don’t need much to feel well. What is your SHBG? Thanks!!!!
 
Ive been using the cream the last two months daily, 1 click/12.5mg AM and 1 click PM. My levels were pretty high like off the charts high TT/FT/DHT so we cut me back from 14mg to 10mg/D.
I have estrogen problems no matter what I do so trying to defer my treatment to DHT this way.
On a 16-79 DHT lab range I can pull about ~100 2hours post application. I saw as high as 155 recently. So I do convert to DHT pretty well with this cream/scrotum method whereas on injections alone my DHT barely hits 40 on that scale.
 

Argus

New Member
Yes, the cream is very powerful. I had the same experience, and gradually reduced my dose down to AM: 1 click (50mg) scrotum / 1 click upper inner thighs, PM: 1/2 click scrotum / 1/2 click upper inner thighs. This puts my total T around 1100 and Free T around 45. Doing the lower dose at night helps with sleep. I initially had some some of the same waking up, anxiety, short fuse issues, but figured out it was liver related and have been doing much better since adding liver support.
 

Argus

New Member
Not to derail the thread... but why dose @ night?
I've read a few folks here who do that, I just do 2-3 clicks in the AM

Because of the short half-life, some people dip low enough overnight that it makes it hard to get out of bed in the morning. I prefer to just take a small dose at night to get me through to the AM.
 

Gunga

Member
Not to derail the thread... but why dose @ night?
I've read a few folks here who do that, I just do 2-3 clicks in the AM

I’m sure everyone is different but anything more than 1 click 50% scrotum/ 50% back of knees get my levels too high. And I can feel it. I just don’t tolerate high levels well. I get puffy. Flushed. Heart pounds through my chest. Etc.
 

wondering

Active Member
Ive been using the cream the last two months daily, 1 click/12.5mg AM and 1 click PM. My levels were pretty high like off the charts high TT/FT/DHT so we cut me back from 14mg to 10mg/D.
I have estrogen problems no matter what I do so trying to defer my treatment to DHT this way.
On a 16-79 DHT lab range I can pull about ~100 2hours post application. I saw as high as 155 recently. So I do convert to DHT pretty well with this cream/scrotum method whereas on injections alone my DHT barely hits 40 on that scale.

Have you seen subjective improvements? If so, how quickly did they arrive.
 

VacationMan

Active Member
Be careful with scrotal application of testosterone cream. I tried it out because my DHT levels were on the low side. While it did help boost DHT into normal range, it also spiked PSA. I'm normally a 1.4 -1.7 PSA. During application of the scrotal test cream, PSA spiked almost to 4.0. Discontinued use as a result. PSA back down to normal levels now.
 

Gunga

Member
Whoa! Ungood! Thanks VacationMan! I’m curious to see my PSA I too this week which will be my first since being on cream. I’ll update you guys on those labs. Thanks!
 
Be careful with scrotal application of testosterone cream. I tried it out because my DHT levels were on the low side. While it did help boost DHT into normal range, it also spiked PSA. I'm normally a 1.4 -1.7 PSA. During application of the scrotal test cream, PSA spiked almost to 4.0. Discontinued use as a result. PSA back down to normal levels now.
False positive? Did you have a DRE or anything other kind of exam to verify that blood test result?
 
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