Testosterone now 700+ and I still feel like crap, what's next?

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Racer33

New Member
Briefing I'm a 33 year old male I started having libido swings In 2015 while my wife was pregnant but no erection issue. Weeks of my usual high libido then a week of low libido And about 9 months later I experienced Ed out of the blue so I went to my urologist and he put me on 25mg of clomid because my testosterone was in the 200 range and about 2-4 weeks later I felt like my self again no ed and no libido issue but suddenly it stopped working after only 2-3 weeks so I called my urologist and he said try taking a whole pill so I did and my libido and erections came back then it eventually stopped again 2-4 weeks later. So I got my testosterone checked again and it was at 550 so he told me to keep taking the clomid so 6 months later I did a follow up and testosterone was at 599 but I was still having erection issues mainly losing erections during sex. So fast forward to this year I started with defy and did blood work and everything looked good except for my growth hormone levels were at 92 and I was told it should be in the 200 range and my estrogen was at 56. They said everything should come back to normal once I get my estrogen down so I was Prescribed Anastrozole so I took 0125 mg everyday for 3 months but erections were the same so I didnt think it was working. Along with erection issues I feel really stiff even though I go to the gym 3-4 days a week my legs dont feel as strong as they were, I feel depressed, anxiety, I'm having a hard time losing weight but gaining weight seems easy, brain fog sometimes I forget what I'm saying in a conversation, I tried lifting weights but didnt really seem like I was gaining muscle,etc.
So I had my labs done again with defy and they checked everything but added t3 and t4. My testosterone is now at 717 on a 264-916 scale, free Testosterone was a 30.0 on a 8.7-25.1 scale and my estrogen is at 23.9 on a 8.0-35.0 scale . IGF-1 is at 85 (went down). T3 was at 3.0 on a 2.0-4.4 scale. T4 was a .90 on a .82-1.77 scale. TSH was 2.320 on a .450 - .4500 scale. He said my t4 was low which could cause some my symptoms also.
I was told to discontinue using clomid and anastrozole try growth hormone medication and a medication to help with my thyroid. So I asked what is my testosterone going to do and he said it will go down but I can try taking testosterone shots to see if I feel better in 2-3 months. But my issue is if my testosterone is 717 now and estrodiol is at a good point what good would a shot do for me. I heard the shot is a forever thing so I'm reallly trying to avoid it. I asked if the low igf-1 could be causing my erection issues and was told probably not. I feel like if I stop taking the med I'd be giving up on myself. What would you do next? Any advice will be highly appreciated.

I must note that I once stopped taking clomid in 2017 but I'm not sure how long I was off of it maybe a month or 2 but my testosterone dropped to 350 range and my estrodiol was at 53 and LH was 9.4. So I started back on clomid and my testosterone raised to 550 range and it stayed there until I started with defy 4 months ago but I didnt check estrodiol because my urologist would not check it.

So far I've been off clomid for 8 days and I feel pretty much the same except for frequent urination that started on the 7th day. Defy said everything looks good on paper but clomid can be tricky.
 
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krm

Member
Did you ever have your cortisol levels checked?
Can you exclude issues on the psychological side - burn-out, stress at work or at home, etc.?
 

Racer33

New Member
Never had cortisol levels checked, what effects does it have on ed. It could be psychological since I've been dealing with this for 2 years hit and miss. I can get a better erection masturbating most of the time but just like in sex it tries to go down pretty quick without stimulation. Cialis once worked great but it started to become hit and miss seemed like I'd get more random erections at work or just by hugging my wife vs when it's time to actually have a erection. I can have a erection during 4 play but when its time to penetrate I'm at 50%. Defy told me I could also try trimax in the mean time or give trt test run. I'm not sure what the clomid did to me in the first 4-6 weeks of treatment but I'd like to feel like that once again.
 
Overdose of Clomid and the number 1 side effect therein is Estrogen. Clomid directly stims the testes and the adjunct factor there is Estrogen, and an AI is much less effective in the testicular environment. You could/would do better on 12.5mg of Clomid EOD, or even daily, but 25mg/D (or more) is far too much.
 
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