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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone in Atrevis hydrogel base = almost double test levels!
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<blockquote data-quote="madman" data-source="post: 200334" data-attributes="member: 13851"><p>A 25 mg dose maintained serum T concentration within the physiological range for almost 24 h.</p><p></p><p>Most men are using much higher doses such as 100-200 mg/application.</p><p></p><p>Where your SHBG sits, the dose used, and how well you absorb the T will have a significant impact on TT/FT level achieved.</p><p></p><p>Even then the only way to know where your T level truly sits on such protocol (once daily scrotal AM application) is to test at peak (2 hrs post-application) and true trough (24 hrs).</p><p></p><p>If you are willing to spend the $$$ I would test at 2 hrs, and 24 hrs post-application, and in order to do such, you would need to apply the T cream around 9 am.</p><p></p><p>Would be interesting to see where levels sit at 2 hr, 12 hr, and 24 hr but highly doubtful any labs operate from 7 am-9 pm.</p><p></p><p></p><p></p><p></p><p><strong>DISCUSSION</strong></p><p><strong></strong></p><p><em>This study provides a pharmacokinetic profile of three doses of testosterone administered to the scrotal skin in a cream formulation. <u>Application of the testosterone cream produced a rapid rise in serum testosterone peaking around 2 h after administration</u> with a dose-dependent peak concentration, but not any consistent relationship between time of peak and testosterone dose.</em> <em><u>At the lowest dose (12.5 mg), the serum testosterone concentrations were maintained in the physiological range for at least 12 h and</u></em><strong><em><u> with the 25 mg dose maintained serum testosterone concentrations within the physiological range for nearly 24 h concentration</u>.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 200334, member: 13851"] A 25 mg dose maintained serum T concentration within the physiological range for almost 24 h. Most men are using much higher doses such as 100-200 mg/application. Where your SHBG sits, the dose used, and how well you absorb the T will have a significant impact on TT/FT level achieved. Even then the only way to know where your T level truly sits on such protocol (once daily scrotal AM application) is to test at peak (2 hrs post-application) and true trough (24 hrs). If you are willing to spend the $$$ I would test at 2 hrs, and 24 hrs post-application, and in order to do such, you would need to apply the T cream around 9 am. Would be interesting to see where levels sit at 2 hr, 12 hr, and 24 hr but highly doubtful any labs operate from 7 am-9 pm. [B]DISCUSSION [/B] [I]This study provides a pharmacokinetic profile of three doses of testosterone administered to the scrotal skin in a cream formulation. [U]Application of the testosterone cream produced a rapid rise in serum testosterone peaking around 2 h after administration[/U] with a dose-dependent peak concentration, but not any consistent relationship between time of peak and testosterone dose.[/I] [I][U]At the lowest dose (12.5 mg), the serum testosterone concentrations were maintained in the physiological range for at least 12 h and[/U][/I][B][I][U] with the 25 mg dose maintained serum testosterone concentrations within the physiological range for nearly 24 h concentration[/U].[/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Testosterone in Atrevis hydrogel base = almost double test levels!
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