This is from Gil T, a clinician from ElecatevMen’s Clinic and a moderator in the Trt and Hormone Optimization Facebook group. He is a super sharp guy and you can find many videos featuring him on the YouTube channel. I was looking back through old posts on here about which pharmacies have the best creams and everyone blasted a guy for assuming the creams were difficult to compound efficiently and only variable would be how one absorbs the product.
“So I have experimented with this and interviewed 3 compounders on it.
First, inconsistency was noted in the way it was milled. One compounder milled once by hand and the other milled twice by hand. The larger one, milled by machine for consistency.
Next was the base. Different bases had a variance on absorption for different patients.
Then there is concentration. A 100mg/ml or a 200mg/ml will absorbe differently as surface area will differ.
Lastly, pharmacokinetics differ by patient and it begins with absorption. We have found Empower to have the best consistency with creams. Perhaps Shaun Noorian can add feedback on the above.”
“So I have experimented with this and interviewed 3 compounders on it.
First, inconsistency was noted in the way it was milled. One compounder milled once by hand and the other milled twice by hand. The larger one, milled by machine for consistency.
Next was the base. Different bases had a variance on absorption for different patients.
Then there is concentration. A 100mg/ml or a 200mg/ml will absorbe differently as surface area will differ.
Lastly, pharmacokinetics differ by patient and it begins with absorption. We have found Empower to have the best consistency with creams. Perhaps Shaun Noorian can add feedback on the above.”
