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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Testosterone and meibomian gland (eyelid) dysfunction
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<blockquote data-quote="madman" data-source="post: 202638" data-attributes="member: 13851"><p><strong>Figure 1 Schematic diagram of the action of androgen on gene expressions of meibomian gland acinar cells Testosterone can be converted to the more active DHT by local 5α-reductase (5α-R) in meibomian gland acinar cells. Both forms of androgen are able to activate AR located in the cytoplasm. The ligand-activated ARs then form dimers and recognize specific regions of DNA after entering the cell nucleus to regulate gene expressions. <u>Genes associated with lipid metabolism and cell keratinization processes are found to be key responders among >1000 genes found to be regulated by androgen in the meibomian gland</u>.</strong></p><p><strong>[ATTACH=full]14664[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 202638, member: 13851"] [B]Figure 1 Schematic diagram of the action of androgen on gene expressions of meibomian gland acinar cells Testosterone can be converted to the more active DHT by local 5α-reductase (5α-R) in meibomian gland acinar cells. Both forms of androgen are able to activate AR located in the cytoplasm. The ligand-activated ARs then form dimers and recognize specific regions of DNA after entering the cell nucleus to regulate gene expressions. [U]Genes associated with lipid metabolism and cell keratinization processes are found to be key responders among >1000 genes found to be regulated by androgen in the meibomian gland[/U]. [ATTACH type="full"]14664[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Testosterone and meibomian gland (eyelid) dysfunction
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