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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Successful Story with Testosterone Cream Protocol
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<blockquote data-quote="Fortunate" data-source="post: 200289" data-attributes="member: 42264"><p>I have been posting on an off about cream. About two months ago, I started with 50mg to scrotum, 50mg to shoulder in AM and another 50mg to shoulder in PM. Felt great initially, but started to have an ”over the top feeling” on that, so I started to back off. </p><p></p><p>I played with various strength creams (150 and 200) at various locations in various combinations. I came to a few conclusions:</p><ul> <li data-xf-list-type="ul">I seemed to reach a max concentration of something (T or DHT) about 8-10 hours after a morning application <ul> <li data-xf-list-type="ul">This confused me, as I thought max concentration was around 2 hours later. But, there is a pharmacokinetic article published in 2017 in the journal <u>Andrology</u> that everyone tends to cite when discussing scrotal absorption. The article actually quotes another study that has shown peak T concentrations can be 6-16 hours after application when applied to non-scrotal skin</li> <li data-xf-list-type="ul">This may explain why I felt the effects of the cream in the late afternoon/early evening</li> </ul></li> <li data-xf-list-type="ul">After the initial honeymoon, I got to a point when even small doses gave me an “over the top” feeling late in the day (rapid heart rate, a touch of a head rush, etc.)</li> </ul><p>I have not gotten bloodwork after using cream, but I suspect that even at low doses, I was probably uncomfortably supraphysiologic</p><p></p><p>To Gerardo’s question, scrotal application has very high absorption rates compared to the arms, so I would be careful. Pay attention to your symptoms and get bloodwork after starting your protocol. In my case, I was using 50mg on the scrotum and another 50 on the shoulder and it felt like it was too much. 30mg doesn’t seem unreasonable, but I know nothing about the product or the base it’s in.</p><p></p><p>For myself, I would not rule out trying some lower dose, maybe on the shoulder only. But, for now, it’s back to Natesto for me (gentle, easy, quick and easy to stop if I want to try something else).</p></blockquote><p></p>
[QUOTE="Fortunate, post: 200289, member: 42264"] I have been posting on an off about cream. About two months ago, I started with 50mg to scrotum, 50mg to shoulder in AM and another 50mg to shoulder in PM. Felt great initially, but started to have an ”over the top feeling” on that, so I started to back off. I played with various strength creams (150 and 200) at various locations in various combinations. I came to a few conclusions: [LIST] [*]I seemed to reach a max concentration of something (T or DHT) about 8-10 hours after a morning application [LIST] [*]This confused me, as I thought max concentration was around 2 hours later. But, there is a pharmacokinetic article published in 2017 in the journal [U]Andrology[/U] that everyone tends to cite when discussing scrotal absorption. The article actually quotes another study that has shown peak T concentrations can be 6-16 hours after application when applied to non-scrotal skin [*]This may explain why I felt the effects of the cream in the late afternoon/early evening [/LIST] [*]After the initial honeymoon, I got to a point when even small doses gave me an “over the top” feeling late in the day (rapid heart rate, a touch of a head rush, etc.) [/LIST] I have not gotten bloodwork after using cream, but I suspect that even at low doses, I was probably uncomfortably supraphysiologic To Gerardo’s question, scrotal application has very high absorption rates compared to the arms, so I would be careful. Pay attention to your symptoms and get bloodwork after starting your protocol. In my case, I was using 50mg on the scrotum and another 50 on the shoulder and it felt like it was too much. 30mg doesn’t seem unreasonable, but I know nothing about the product or the base it’s in. For myself, I would not rule out trying some lower dose, maybe on the shoulder only. But, for now, it’s back to Natesto for me (gentle, easy, quick and easy to stop if I want to try something else). [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Successful Story with Testosterone Cream Protocol
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