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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Subcutaneous Testosterone Injections Are A Good Alternative to Intramuscular Ones
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<blockquote data-quote="the_shep" data-source="post: 86064" data-attributes="member: 16899"><p><strong>Abstract</strong></p><p></p><p>Context:</p><p>Testosterone (T) is commonly administered intramuscularly to treat hypogonadal males and female-to-male (FTM) transgender patients. However, these injections can involve significant discomfort and may require arrangements for administration by others.</p><p></p><p>Objective:</p><p>We assessed whether T could be administered effectively and safely subcutaneously as an alternative to intramuscular (IM) injections.</p><p></p><p>Two preliminary reports (10, 11) and a pharmacokinetic study (12) of SC T administration suggest that the SC route may be a safe, convenient, and effective alternative to currently available options. The preliminary reports assessed short-term therapy in hypogonadal men (10) and FTM transgender patients (11) and did not universally attain serum levels of T within the normal range. The pharmacokinetic study used fixed doses from a potentially expensive autoinjector (12). To further characterize SC T as a practical and acceptable alternative to IM administration, we evaluated the efficacy, safety, and acceptability of manual SC injections of T cypionate to patients undergoing FTM sex transition in our clinic.</p><p></p><p><a href="https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2017-00359" target="_blank">Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients</a></p><p></p><p>Apologies if this has been posted previously.</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/how-to-inject-testosterone-intramuscularly-shallow-im-or-subcutaneously.8858/[/URL]</p></blockquote><p></p>
[QUOTE="the_shep, post: 86064, member: 16899"] [B]Abstract[/B] Context: Testosterone (T) is commonly administered intramuscularly to treat hypogonadal males and female-to-male (FTM) transgender patients. However, these injections can involve significant discomfort and may require arrangements for administration by others. Objective: We assessed whether T could be administered effectively and safely subcutaneously as an alternative to intramuscular (IM) injections. Two preliminary reports (10, 11) and a pharmacokinetic study (12) of SC T administration suggest that the SC route may be a safe, convenient, and effective alternative to currently available options. The preliminary reports assessed short-term therapy in hypogonadal men (10) and FTM transgender patients (11) and did not universally attain serum levels of T within the normal range. The pharmacokinetic study used fixed doses from a potentially expensive autoinjector (12). To further characterize SC T as a practical and acceptable alternative to IM administration, we evaluated the efficacy, safety, and acceptability of manual SC injections of T cypionate to patients undergoing FTM sex transition in our clinic. [URL="https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2017-00359"]Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients[/URL] Apologies if this has been posted previously. [URL unfurl="true"]https://www.excelmale.com/forum/threads/how-to-inject-testosterone-intramuscularly-shallow-im-or-subcutaneously.8858/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Subcutaneous Testosterone Injections Are A Good Alternative to Intramuscular Ones
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