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General Health & Fitness
Nutrition and Supplements
Stop taking Vitamin D already
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<blockquote data-quote="Mastodont" data-source="post: 229704" data-attributes="member: 43770"><p>It would be nice to have a survey, where you would have fat and thin people tested, i am pretty sure both groups would be deficient nowadays.</p><p>Now i am not sure those differences are significant;</p><p></p><p>Leptin concentration decreased from 16.90 ± 1.65 ng/ml to 14.72 ± 1.78 ng/ml and TMAO concentration from 63.41 ± 12.59 ng/ml to 59.98 ± 12.36 ng/ml. A significant increase in VEGF-A (298.81 ± 27.44 vs. 322.91 ± 26.02 pg/ml), NO (39.19 ± 10.96 vs. 70.02 ± 13.80 µmol/l) and 25(OH)D serum levels (18.22 ± 1.10 vs. 29.89 ± 1.16 ng/ml) was observed (Fig. <a href="https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-022-00666-4#Fig2" target="_blank">2</a>). </p><p></p><p>This however at 2000iu is a great encouragement for many who think more is better, wish they also had one group only doing 1000iu to compare.</p><p>Long term safety of isolated d supplementation remains to be seen.</p></blockquote><p></p>
[QUOTE="Mastodont, post: 229704, member: 43770"] It would be nice to have a survey, where you would have fat and thin people tested, i am pretty sure both groups would be deficient nowadays. Now i am not sure those differences are significant; Leptin concentration decreased from 16.90 ± 1.65 ng/ml to 14.72 ± 1.78 ng/ml and TMAO concentration from 63.41 ± 12.59 ng/ml to 59.98 ± 12.36 ng/ml. A significant increase in VEGF-A (298.81 ± 27.44 vs. 322.91 ± 26.02 pg/ml), NO (39.19 ± 10.96 vs. 70.02 ± 13.80 µmol/l) and 25(OH)D serum levels (18.22 ± 1.10 vs. 29.89 ± 1.16 ng/ml) was observed (Fig. [URL='https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-022-00666-4#Fig2']2[/URL]). This however at 2000iu is a great encouragement for many who think more is better, wish they also had one group only doing 1000iu to compare. Long term safety of isolated d supplementation remains to be seen. [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
Stop taking Vitamin D already
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