Someone with low shbg had little/no success with once/twice week injection, but ED/EOD?

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equel

Active Member
17-21 SHBG here, so fucking random mood, energy, libido usually gone, sometimes there, erections sometimes hard, many times weak.

Done weekly and 2 times a week injections, all kinds of arimidex protocol and it just doesnt fucking work.



Thinking of trying ED or EOD injections, anyone had success? Im so tired of this and im very, very frustrated.
 
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Systemlord

Member
I'm a low SHBG guy also and about the same numbers as you. I'll tell you I felt way, way better on a daily protocol then I did and EOD protocols. I felt no fluctuations during the 1st 6 weeks on a daily protocol, it was an easily smooth ride.

And EOD protocol induces swings that are not pleasant and if I could do without them I would, but I cannot. I didn't feel much injecting once or twice weekly either.

I use 29G insulin syringes.
 
I'm a low SHBG guy also and about the same numbers as you. I'll tell you I felt way, way better on a daily protocol then I did and EOD protocols. I felt no fluctuations during the 1st 6 weeks on a daily protocol, it was an easily smooth ride.

And EOD protocol induces swings that are not pleasant and if I could do without them I would, but I cannot. I didn't feel much injecting once or twice weekly either.

I use 29G insulin syringes.

I started out with 29 g 1/2 inch insulin syringes and always bruised or had the small lump , injected mon morning ,wed night , sat morning stomach and love handles , never failed bruising or noticible lumps….also with it taking longer to inject the needle would move around irritating the inside of my fat/skin to cause pip , and if I trie to inject quicker it would bruise cause the oil comes out like a pressure washer cause of the small end .

Whats your trick to not having any of the negative affects above .

I switched to 25 guage 5/8 and its working great stomach and love handles .
 

fifty

Well-Known Member
Anything above 27g drives me crazy for oil based products. I’d rather not spend minutes to draw & inject.
 
17-21 SHBG here, so fucking random mood, energy, libido usually gone, sometimes there, erections sometimes hard, many times weak.

Done weekly and 2 times a week injections, all kinds of arimidex protocol and it just doesnt fucking work.



Thinking of trying ED or EOD injections, anyone had success? Im so tired of this and im very, very frustrated.

This forum has an excellent search engine, if you search things like low SHBG protocols you'll get a plethora of useful information.
 

tcmi

Member
I’ve got very low SHBG (usually 13-18). Tried weekly, 3x week, EOD and daily injections. Tried test cream on scrotum. Tried all different iterations of HCG doses and timing. Tried all different iterations of AI doses and timing. After 3-4 years of experimenting, and lots of lab work, I’ve settled into something very simple that works very well. 30-32mg test cyp injected EOD. No HCG, No AI. 30mg pregnenolone per day. The wild swings are gone and I feel excellent. Total/Free was last tested 1044/365 24 hours post injection, 803/242 48 hours post injection (immediately prior to next injection). Estradiol was 49, ultrasensitive was 66 (both tests done same draw). No side effects. At least for me, I really think it was the effects of HCG and AI that were causing my issues.
 

Ardoc2

Member
I have very low SHBG (15.8 Range: 19.0 - 76.0 nmol/L). I can't say I had "little/no success" on less frequent injections but I settled on daily about a year ago and it has been the best I've felt since starting TRT over 6 years ago. When on less frequent injections I typically had to donate blood to keep HCT in check but no longer have to (coincidence?) but now I take 22mg Test Cyp/day with no AI (E2 has never been an issue for me). This puts me close to top range for Total Test and about 30% over range for Free Test. Every day is definitely right for me.
 

Cataceous

Super Moderator
... Total/Free was last tested 1044/365 24 hours post injection, 803/242 48 hours post injection (immediately prior to next injection). ...
It's interesting to run the numbers when there's data like this. Assuming no measurement errors, these values suggest your half-life for T cypionate is about 5.5 days.
 

equel

Active Member
I’ve got very low SHBG (usually 13-18). Tried weekly, 3x week, EOD and daily injections. Tried test cream on scrotum. Tried all different iterations of HCG doses and timing. Tried all different iterations of AI doses and timing. After 3-4 years of experimenting, and lots of lab work, I’ve settled into something very simple that works very well. 30-32mg test cyp injected EOD. No HCG, No AI. 30mg pregnenolone per day. The wild swings are gone and I feel excellent. Total/Free was last tested 1044/365 24 hours post injection, 803/242 48 hours post injection (immediately prior to next injection). Estradiol was 49, ultrasensitive was 66 (both tests done same draw). No side effects. At least for me, I really think it was the effects of HCG and AI that were causing my issues.

Thankyou mate and thanks everyone else for your posts, may I ask how your libido is?


Today I started 20 ED protocol of test C.
 

equel

Active Member
I have very low SHBG (15.8 Range: 19.0 - 76.0 nmol/L). I can't say I had "little/no success" on less frequent injections but I settled on daily about a year ago and it has been the best I've felt since starting TRT over 6 years ago. When on less frequent injections I typically had to donate blood to keep HCT in check but no longer have to (coincidence?) but now I take 22mg Test Cyp/day with no AI (E2 has never been an issue for me). This puts me close to top range for Total Test and about 30% over range for Free Test. Every day is definitely right for me.

How is libido mate?
 

Ardoc2

Member
Very good... but to be fair that was not one of the reasons I sought out TRT. Prior to starting I had no issues (that I knew of) with libido but in fact it must have waned slowly over time because it did improve significantly on TRT. It's the best on daily protocol for me!
 

Tman

Active Member
I'm a low SHBG guy also and about the same numbers as you. I'll tell you I felt way, way better on a daily protocol then I did and EOD protocols. I felt no fluctuations during the 1st 6 weeks on a daily protocol, it was an easily smooth ride.

And EOD protocol induces swings that are not pleasant and if I could do without them I would, but I cannot. I didn't feel much injecting once or twice weekly either.

I use 29G insulin syringes.
How much t??
 

Robotics

Active Member
I’ve got very low SHBG (usually 13-18). Tried weekly, 3x week, EOD and daily injections. Tried test cream on scrotum. Tried all different iterations of HCG doses and timing. Tried all different iterations of AI doses and timing. After 3-4 years of experimenting, and lots of lab work, I’ve settled into something very simple that works very well. 30-32mg test cyp injected EOD. No HCG, No AI. 30mg pregnenolone per day. The wild swings are gone and I feel excellent. Total/Free was last tested 1044/365 24 hours post injection, 803/242 48 hours post injection (immediately prior to next injection). Estradiol was 49, ultrasensitive was 66 (both tests done same draw). No side effects. At least for me, I really think it was the effects of HCG and AI that were causing my issues.

why did you start suplementing pregnenolone? were your levels low? and what benefits did you find? How is your sexual function/libido with a low shbg and such a high E2?
 

tcmi

Member
why did you start suplementing pregnenolone? were your levels low? and what benefits did you find? How is your sexual function/libido with a low shbg and such a high E2?

Started pregnenolone in January immediately after stopping HCG and AI. I had done testing for pregnenolone and my number was at the bottom of the Quest range. Hard to know exactly what’s its doing vs. stopping HCG/AI. I do know that I tried increasing pregnenolone from 30mg 1x day to 50mg 1x day and didn’t like how it made me feel so I went back to 30mg. I also take Vitamin D/K, Magnesium, probiotics and a high quality B complex. Libido / erections are fine at current E levels. I occasionally use 20mg Viagra but really don’t need it.
 

Cyclingislife

New Member
I’ve got very low SHBG (usually 13-18). Tried weekly, 3x week, EOD and daily injections. Tried test cream on scrotum. Tried all different iterations of HCG doses and timing. Tried all different iterations of AI doses and timing. After 3-4 years of experimenting, and lots of lab work, I’ve settled into something very simple that works very well. 30-32mg test cyp injected EOD. No HCG, No AI. 30mg pregnenolone per day. The wild swings are gone and I feel excellent. Total/Free was last tested 1044/365 24 hours post injection, 803/242 48 hours post injection (immediately prior to next injection). Estradiol was 49, ultrasensitive was 66 (both tests done same draw). No side effects. At least for me, I really think it was the effects of HCG and AI that were causing my issues.
I’m in the same boat as you with low shbg. Do you inject IM or SubQ? Are you still on 30-32mg EOD?
 

tcmi

Member
I inject into muscle with 1/2” needle. Some call this shallow IM. I did switch to daily shots but recently went back to EOD.
 
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