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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Should I lower my TRT dose?
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<blockquote data-quote="Cataceous" data-source="post: 208133" data-attributes="member: 38109"><p>You previously said "... there is an ester attached to this testosterone that <u>you conveniently miss</u>." You didn't explain where it was missed. In fact it wasn't, and your error betrays a questionable comprehension of the subject.</p><p></p><p></p><p>35 nMol/L of testosterone is effectively supraphysiological when SHBG is normal or low. Use any free T calculator to verify that free testosterone is excessive in these cases. For example, Tru-T with TT of 1,000 ng/dL and SHBG of 30 nMol/L yields FT of over 36 ng/dL. This is above the normal range that tops out at 31 ng/dL. The guys who naturally have such high total testosterone almost always have high SHBG. High SHBG drives up total testosterone even when the production rate is normal. 46 nMol/L of total testosterone is supraphysiological, period.</p><p></p><p>You offer no proof that the test ranges are flawed. We have population studies from decades ago to compare to. You're just trying to normalize high serum levels to justify your excessive dosing, which you laughably describe as "optimizing". It's your body, so you are free to experiment as you like. But don't pretend that you have any idea about the long-term safety of high levels, and don't discourage others from starting with more reasonable levels. Doing otherwise is irresponsible.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 208133, member: 38109"] You previously said "... there is an ester attached to this testosterone that [U]you conveniently miss[/U]." You didn't explain where it was missed. In fact it wasn't, and your error betrays a questionable comprehension of the subject. 35 nMol/L of testosterone is effectively supraphysiological when SHBG is normal or low. Use any free T calculator to verify that free testosterone is excessive in these cases. For example, Tru-T with TT of 1,000 ng/dL and SHBG of 30 nMol/L yields FT of over 36 ng/dL. This is above the normal range that tops out at 31 ng/dL. The guys who naturally have such high total testosterone almost always have high SHBG. High SHBG drives up total testosterone even when the production rate is normal. 46 nMol/L of total testosterone is supraphysiological, period. You offer no proof that the test ranges are flawed. We have population studies from decades ago to compare to. You're just trying to normalize high serum levels to justify your excessive dosing, which you laughably describe as "optimizing". It's your body, so you are free to experiment as you like. But don't pretend that you have any idea about the long-term safety of high levels, and don't discourage others from starting with more reasonable levels. Doing otherwise is irresponsible. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Should I lower my TRT dose?
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