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General Health & Fitness
Nutrition and Supplements
SAMe Improves Fatigue, Depression, and Protects the Liver
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<blockquote data-quote="BigTex" data-source="post: 218627" data-attributes="member: 43589"><p>They just list SAMe as contradicted to bipolar disease. However there is being a clinical trial done to see if it is possible to treat bipolar with SAMe</p><p></p><p>Here is the description:</p><p></p><p>Depression in bipolar disorder is a significant source of disease-related debility; with bipolar individuals typically spending three fold as much time depressed as manic or hypomanic. Clinicians treating bipolar disorder often struggle to provide relief from depressive symptoms that are more often treatment resistant than in unipolar depression. To complicate matters further, the risk/benefit ratio of currently available antidepressants is a source of debate within the field of psychiatry.</p><p></p><p>S-adenosyl-L-methionine (SAMe) is a dietary supplement with well-established antidepressant properties. SAMe's mechanism of action remains unclear, but it appears to be distinct from that of conventional antidepressants. The purpose of this study is to examine the effect of these properties on the mood of bipolar subjects with persistent major depression that has been unresponsive to standard pharmacotherapy.</p></blockquote><p></p>
[QUOTE="BigTex, post: 218627, member: 43589"] They just list SAMe as contradicted to bipolar disease. However there is being a clinical trial done to see if it is possible to treat bipolar with SAMe Here is the description: Depression in bipolar disorder is a significant source of disease-related debility; with bipolar individuals typically spending three fold as much time depressed as manic or hypomanic. Clinicians treating bipolar disorder often struggle to provide relief from depressive symptoms that are more often treatment resistant than in unipolar depression. To complicate matters further, the risk/benefit ratio of currently available antidepressants is a source of debate within the field of psychiatry. S-adenosyl-L-methionine (SAMe) is a dietary supplement with well-established antidepressant properties. SAMe's mechanism of action remains unclear, but it appears to be distinct from that of conventional antidepressants. The purpose of this study is to examine the effect of these properties on the mood of bipolar subjects with persistent major depression that has been unresponsive to standard pharmacotherapy. [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
SAMe Improves Fatigue, Depression, and Protects the Liver
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