New Testosterone Nasal Spray Offers Patients an Alternative

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madman

Super Moderator
New Testosterone Nasal Spray Offers Patients an Alternative - UT News






AUSTIN, TexasA newly patented, testosterone-containing nasal spray developed by a psychology professor at The University of Texas at Austin could provide those suffering from testosterone deficiency and other ailments, such as anxiety disorders, with easily modulated, fast-acting results.


The new aqueous-based nasal spray was initially developed to address a current market need for comfortable and controlled dosages of testosterone for people suffering from decreased libido and anxiety disorders. Testosterone is in high demand with prescriptions increasing fivefold since 2011.


“A growing body of research points to testosterone’s importance in the etiology of anxiety disorders. These findings highlight the potential benefit of rapid increases in testosterone concentration as a means to short-circuit the mechanisms underlying the development of anxiety-related disorders, including panic disorder, social anxiety and PTSD,” said Josephs, who is also an adjunct professor of psychiatry at the Dell Medical School.


Although testosterone is not currently prescribed for anxiety, Josephs hopes that treating anxiety disorders with a short-term, fast-acting testosterone product might be prescribed alongside a lower dose of benzodiazepines — such as Xanax or Klonopin.


“Although benzodiazepines work well, they have strong sedative effects,” Josephs said. “Testosterone is not sedating.”
 
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madman

Super Moderator
Screenshot (553).png

The aqueous-based nasal spray was initially developed to address a current market need for comfortable and controlled dosages of testosterone for people suffering from "low T."
 

Rain27

Member
Lamentablemente en mi pais estamos años luz de estas presentaciones , cuantos de nosotros hubiesemos querido empezar TRT con Natesto por ejemplo y no podemos acceder porque simplemente no existe por estas latitudes .
 

madman

Super Moderator
Is this natesto?




No it is an aqueous solution (spray) as oppose to NATESTO® which is a gel.


UT Austin psychology professor Robert Josephs and MedCara Pharmaceuticals pharmacist Craig Herman developed their nasal spray in response to a long-standing research question about why women are twice as likely as men to develop anxiety disorders.



Effects of Fast Acting Testosterone Nasal Spray on Anxiety - Full Text View - ClinicalTrials.gov




O12. Intranasal Testosterone Reduces Stress-Evoked Anxiety in Women

Ellie Shuo Jin and Robert Alan Josephs

The University of Texas at Austin





Background: Can a single-dose of a testosterone-containing nasal spray reduce anxiety? Although both exogenous and endogenous testosterone have been associated with reductions in implicitly measured fear responses, it remains unknown whether exogenous testosterone can reduce the explicit, subjective experience of anxiety in humans


Methods: In the present study, participants (N ¼ 104, 48.1% female) were randomly assigned to receive either testosterone or placebo via intranasal spray before taking part in an acute psychosocial stressor. Participants used visual analogue scales to rate their subjective anxiety before, during, and after the stressor.


Results: Results revealed a statistically significant drug by sex interaction, in which women as expected experienced significantly higher levels of subjective anxiety in the placebo condition compared to men; a sex difference that was eliminated in the drug condition. Further, women randomized to the testosterone condition experienced significantly lower levels of anxiety during recovery from the acute stressor relatively to women in the placebo condition.


Conclusions: Taken together, these results have important implications for the etiology of anxiety and treatment.








The nasal spray (United States Patent No. 10,258,63, issued on April 16, 2019) has been licensed to Acerus Pharmaceuticals Corporation, which has the flexibility under the current agreement to use the technology in whatever medical field it deems most appropriate.
 

madman

Super Moderator
Interesting point is that this newly patented nasal spray has been licensed to Acerus Pharmaceuticals Corporation.....the same pharmaceutical company which has the exclusive rights to manufacture NATESTO®



*The nasal spray (United States Patent No. 10,258,63, issued on April 16, 2019) has been licensed to Acerus Pharmaceuticals Corporation, which has the flexibility under the current agreement to use the technology in whatever medical field it deems most appropriate.
 

madman

Super Moderator
[QUOTE = "Rain27, post: 158234, member: 38859"] Unfortunately in my country we are light years from these presentations, how many of us would have liked to start TRT with Natesto for example and cannot access because it simply does not exist in these latitudes. [ / QUOTE]






Regarding NATESTO®

Additional patents have been issued or are pending in over 60 more countries worldwide




Screenshot (554).png
 

madman

Super Moderator
[QUOTE = "Rain27, post: 158272, member: 38859"] Crazy can you see if my country is also pending? [/ QUOTE]


You would need to contact Carnot laboratorios to find out the details regarding when it will be available in your country.





https://www.businesswire.com/news/home/20180413005081/en/Acerus-Announces-Licensing-NATESTO®-19-Central-Latin


TORONTO--(BUSINESS WIRE)--Acerus Pharmaceuticals Corporation (TSX:ASP) (“Acerus” or the “Company”) today announced the signing of an agreement granting Producto Científicos, S.A. de C.V (“Carnot Laboratorios”) the exclusive right to market NATESTO® in 19 Central and Latin American countries (Mexico, Argentina, Columbia, Peru, Chile, Ecuador, Guatemala, El Salvador, Nicaragua, Honduras, Panama, Costa Rica, Cuba, Dominican Republic, Venezuela, Bolivia, Uruguay, Paraguay and Haiti). Carnot Laboratorios is a Latin American pharmaceutical company founded in 1941, based in Mexico City and active in Central and Latin American countries directly or via commercial partners. Carnot Laboratorios employs 1,039 employees including 483 sales representatives.








MÉXICO
Nicolás San Juan 1046, Col. Del Valle,
C.P. 03100, Benito Juárez, Ciudad de México, México.
+ 52 (55) 5488-7000
[email protected]


Dudas, sugerencias y quejas:
+ 01800 999 98 98
sin costo desde cualquier parte de la República Mexicana.
El horario de atención es: Lun. a Jue. 8:00 a 18:00 hrs. y Vie. 8:00 a 13:00 hrs.
[email protected]
 

Robotics

Active Member
will this have a similar half life as natesto? I am guessing since it is for anxiety the dosage will be significantly less.
 

madman

Super Moderator
O12. Intranasal Testosterone Reduces Stress-Evoked Anxiety in Women
 

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