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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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<blockquote data-quote="Cataceous" data-source="post: 212555" data-attributes="member: 38109"><p>I'm unclear on the practical implications of these. If androgens are generally increasing aromatization independently via the androgen receptor and this significantly affects estradiol production at physiological levels then I'd think it would affect the outcome of research <a href="https://pubmed.ncbi.nlm.nih.gov/20534765/" target="_blank">like this</a>, and you wouldn't necessarily see a good fit to the saturable Michaelis-Menten kinetics.</p><p></p><p>In any case, it seems like the basics aren't in dispute: If you substitute nandrolone for testosterone then you greatly decrease estradiol. If you add nandrolone to testosterone then you increase estradiol by some amount. The question about the latter is, does the increase come mainly from the extra raw material available for conversion, or does the nandrolone itself stimulate significantly more overall aromatization?</p><p></p><p>I am interested in seeing the size of your estradiol increases with nandrolone...</p></blockquote><p></p>
[QUOTE="Cataceous, post: 212555, member: 38109"] I'm unclear on the practical implications of these. If androgens are generally increasing aromatization independently via the androgen receptor and this significantly affects estradiol production at physiological levels then I'd think it would affect the outcome of research [URL='https://pubmed.ncbi.nlm.nih.gov/20534765/']like this[/URL], and you wouldn't necessarily see a good fit to the saturable Michaelis-Menten kinetics. In any case, it seems like the basics aren't in dispute: If you substitute nandrolone for testosterone then you greatly decrease estradiol. If you add nandrolone to testosterone then you increase estradiol by some amount. The question about the latter is, does the increase come mainly from the extra raw material available for conversion, or does the nandrolone itself stimulate significantly more overall aromatization? I am interested in seeing the size of your estradiol increases with nandrolone... [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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